CAS 73644-43-6

10-[3-(Dimethylamino)propyl]-α-methyl-10H-phenothiazine-2-methanol

Description:

10-[3-(Dimethylamino)propyl]-α-methyl-10H-phenothiazine-2-methanol, with CAS number 73644-43-6, is a chemical compound belonging to the phenothiazine class, which is characterized by a tricyclic structure containing sulfur and nitrogen atoms. This compound features a dimethylamino group, which contributes to its potential as a pharmacological agent, particularly in the field of psychiatry and neurology. The presence of the α-methyl group enhances its lipophilicity, potentially affecting its ability to cross the blood-brain barrier. Additionally, the methanol moiety may influence its solubility and reactivity. Phenothiazines are known for their antipsychotic properties, and this compound may exhibit similar biological activities, including interactions with neurotransmitter systems such as dopamine and serotonin. Its specific pharmacological profile, toxicity, and therapeutic applications would require further investigation through empirical studies. As with many chemical substances, safety data sheets should be consulted for handling and exposure guidelines.

Formula: C₁₉H₂₄N₂OS

InChI: InChI=1S/C19H24N2OS/c1-14(22)15-9-10-19-17(13-15)21(12-6-11-20(2)3)16-7-4-5-8-18(16)23-19/h4-5,7-10,13-14,22H,6,11-12H2,1-3H3

InChI key: InChIKey=ZIJWCRNUEBJMSQ-UHFFFAOYSA-N

SMILES: C(CCN(C)C)N1C=2C(SC=3C1=CC=CC3)=CC=C(C(C)O)C2

Synonyms:

• 10H-Phenothiazine-2-methanol, 10-[3-(dimethylamino)propyl]-α-methyl-
• Phenothiazine-2-methanol, 10-(3-dimethylaminopropyl)-α-methyl-
• 10-[3-(Dimethylamino)propyl]-α-methyl-10H-phenothiazine-2-methanol
• 2-(1-hydroxyethyl)promazine

2-(1-Hydroxyethyl) Promazine

CAS: 73644-43-6

Applications A metabolite of Acepromazine (A130900).
References Cossum, P., et al.: Drug Dispos., 9, 321 (1988), Stowell, L., et al.: J. Anal. Toxicol., 22, 166 (1998),

Formula: C₁₉H₂₄N₂OS

Color and Shape: Neat

Molecular weight: 328.47

Ref: TR-H942295