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CAS 736992-12-4

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9-(Acetylimino)-9-deoxo-3-des(hexopyranosyloxy)-3-oxo-6-O,11-O-[2-[6-(1H-pyrazol-1-yl)pyridin-3-ylmethoxyimino]propylene]erythromycin A

Description:
9-(Acetylimino)-9-deoxo-3-des(hexopyranosyloxy)-3-oxo-6-O,11-O-[2-[6-(1H-pyrazol-1-yl)pyridin-3-ylmethoxyimino]propylene]erythromycin A is a complex macrolide antibiotic derivative, structurally related to erythromycin. This compound features multiple functional groups, including an acetylimino moiety, which contributes to its biological activity. The presence of a hexopyranosyloxy group enhances its solubility and stability, while the pyrazol-1-yl and pyridin-3-ylmethoxyimino substituents suggest potential interactions with biological targets, possibly enhancing its antimicrobial efficacy. The compound's structure indicates it may exhibit a broad spectrum of activity against various bacterial strains, similar to other erythromycin derivatives. Its intricate design suggests potential for use in medicinal chemistry, particularly in developing new antibiotics or modifying existing ones to overcome resistance. As with many macrolides, it is likely to function by inhibiting bacterial protein synthesis, although specific mechanisms and efficacy would require further investigation through experimental studies.
Formula:C43H64N6O11
Synonyms:
  • Modithromycin
  • EDP-420
  • S-013420
  • EP-013420
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