CAS 7370-21-0

Pyridine, 2-methyl-6-[(1E)-2-phenylethenyl]-

Description:

Pyridine, 2-methyl-6-[(1E)-2-phenylethenyl]- is an organic compound characterized by its pyridine ring, which is a six-membered aromatic heterocycle containing one nitrogen atom. This compound features a methyl group at the 2-position and a phenylethenyl group at the 6-position of the pyridine ring, contributing to its unique chemical properties. It is typically a colorless to pale yellow liquid with a distinctive odor, reminiscent of pyridine. The presence of the double bond in the phenylethenyl group introduces reactivity, making it susceptible to electrophilic addition reactions. This compound is likely to exhibit moderate solubility in polar solvents due to the nitrogen atom's ability to engage in hydrogen bonding. Its applications may span various fields, including organic synthesis and materials science, where it can serve as an intermediate or a building block for more complex molecules. Safety precautions should be observed when handling this compound, as it may pose health risks upon exposure.

Formula: C₁₄H₁₃N

SIB 1893

CAS: 7370-21-0

Formula: C₁₄H₁₃N

Molecular weight: 195.26

Ref: 7W-GL9432

SIB-1893

CAS: 7370-21-0

SIB-1893 is a GABA analogue that binds to the gamma-aminobutyric acid receptor and inhibits neuronal death. It has been shown to be neuroprotective in cell culture. SIB-1893 also has potent antagonist effects on glutamate receptors, which may be related to its potential clinical use as an anti-epileptic drug. SIB-1893 does not show any significant binding affinity for other glutamate receptor subtypes, such as AMPA or kainate receptors. The uptake of this drug by cells is dependent on the presence of functional uptake transporters (e.g., GLT1) and the expression levels of these transporters are variable between different cell types. These uptake transporters play an important role in determining the therapeutic efficacy of this drug, since it can only enter cells if they express a functional transporter. Furthermore, SIB-1893 induces necrotic cell death when applied to cultured cells, but apoptotic cell death when injected

Formula: C₁₄H₁₃N

Purity: Min. 95%

Molecular weight: 195.26 g/mol

Ref: 3D-HAA37021

SIB-1893

CAS: 7370-21-0

SIB-1893: mGlu5 receptor non-competitive antagonist, IC50=0.3μM; >100μM for hmGlu1b, 2, 6, 7, 8; mGlu4 positive modulator.

Formula: C₁₄H₁₃N

Color and Shape: Solid

Molecular weight: 195.26

Ref: TM-T68778