CAS 73724-40-0
:Fmoc-Ala-OSu
Description:
Fmoc-Ala-OSu, or Fluorenylmethyloxycarbonyl-Alanine N-hydroxysuccinimide ester, is a chemical compound commonly used in peptide synthesis and bioconjugation. It features a fluorenylmethyloxycarbonyl (Fmoc) protecting group attached to the amino acid alanine, which allows for selective protection of the amino group during peptide synthesis. The N-hydroxysuccinimide (OSu) moiety facilitates the formation of stable amide bonds with nucleophiles, such as amines, making it useful in coupling reactions. Fmoc-Ala-OSu is typically a white to off-white solid and is soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Its stability under standard laboratory conditions allows for ease of handling, although it should be stored in a cool, dry place to prevent degradation. The compound is widely utilized in the field of organic chemistry, particularly in the synthesis of peptides and other biomolecules, due to its efficiency in facilitating the formation of peptide bonds while maintaining the integrity of the amino acid side chains.
Formula:C22H20N2O6
InChI:InChI=1/C22H20N2O6/c1-13(21(27)30-24-19(25)10-11-20(24)26)23-22(28)29-12-18-16-8-4-2-6-14(16)15-7-3-5-9-17(15)18/h2-9,13,18H,10-12H2,1H3,(H,23,28)
SMILES:CC(C(=O)ON1C(=O)CCC1=O)N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:- 2,5-dioxopyrrolidin-1-yl N-[(9H-fluoren-9-ylmethoxy)carbonyl]alaninate
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