CAS 73724-45-5

Fmoc-L-Serine

Description:

Fmoc-L-Serine is a derivative of the amino acid serine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protective group. This compound is commonly used in peptide synthesis as a building block due to its ability to protect the amino group during the coupling process. Fmoc-L-Serine retains the functional properties of serine, including its polar nature and ability to participate in hydrogen bonding, which is crucial for protein structure and function. The Fmoc group is typically removed under basic conditions, allowing for the subsequent formation of peptide bonds. Fmoc-L-Serine is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but its solubility in water is limited. The compound is often utilized in the synthesis of peptides that require serine residues, playing a significant role in the development of pharmaceuticals and bioconjugates. Its CAS number, 73724-45-5, is used for identification in chemical databases and regulatory contexts.

Formula: C₁₈H₁₆NO₅

InChI: InChI=1/C18H17NO5/c20-9-16(17(21)22)19-18(23)24-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16,20H,9-10H2,(H,19,23)(H,21,22)/p-1/t16-/m0/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=N[C@@H](CO)C(=O)[O-])O

Synonyms:

• N-Fmoc-L-serine monohydrate
• Fmoc-L-Ser-OH
• N-(9-Fluorenylmethoxycarbonyl)-L-serine
• Fmoc-Ser-OH
• N-Fmoc-L-serine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine
• (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-hydroxypropanoate

N-Fmoc-L-serine, 97+%

CAS: 73724-45-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₈H₁₇NO₅

Purity: 97+%

Color and Shape: White, Powder

Molecular weight: 327.34

Ref: 02-B21079

Fmoc-Ser-OH · H₂O

CAS: 73724-45-5

Educt for the synthesis of O-glycosylated serine building blocks. Liu et al. synthesized O-mannosylated Fmoc-Ser.

Formula: C₁₈H₁₇NO₅·H₂O

Purity: 99.4%

Color and Shape: White Powder

Molecular weight: 345.35

Ref: 01-4044985

Fmoc-L-Serine

CAS: 73724-45-5

Formula: C₁₈H₁₇NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 327.3313

Ref: IN-DA0036P2

Fmoc-Ser-OH

CAS: 73724-45-5

Fmoc-Ser-OH

Purity: 98%

Molecular weight: 327.33g/mol

Ref: 54-OR1013391

Fmoc-Ser-OH

CAS: 73724-45-5

Formula: C₁₈H₁₇NO₅

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 327.34

Ref: 7W-GM5457

Fmoc-Ser-OH

CAS: 73724-45-5

M03381 - Fmoc-Ser-OH

Formula: C₁₈H₁₇NO₅

Purity: 97.00%

Color and Shape: Crystalline Powder,Powder

Molecular weight: 327.336

Ref: 10-M03381

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-serine

CAS: 73724-45-5

Formula: C₁₈H₁₇NO₅

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 327.34

Ref: 3B-F0454

Fmoc-L-Ser-OH

CAS: 73724-45-5

Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group.
Fmoc-L-Ser has also been shown to have antiestrogenic effects, which may be due to

Formula: C₁₈H₁₇NO₅

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 327.33 g/mol

Ref: 3D-FF33216

FMOC-L-Serine extrapure, 99%

CAS: 73724-45-5

Formula: C₁₈H₁₇NO₅

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 327.34

Ref: SR-18126