CAS 737727-12-7

Benzamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-

Description:

Benzamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro- is a chemical compound characterized by its unique bicyclic structure and the presence of a benzamide functional group. The compound features a bicyclo[2.2.2]octane framework, which contributes to its rigidity and potential biological activity. The azabicyclic structure includes a nitrogen atom, which can influence the compound's interaction with biological targets, potentially affecting its pharmacological properties. The presence of a chloro substituent at the para position of the benzamide moiety may enhance its lipophilicity and alter its reactivity. This compound is of interest in medicinal chemistry, particularly for its potential applications in drug development, as the bicyclic structure is often associated with various biological activities. Its specific stereochemistry, indicated by the (3S) designation, may also play a crucial role in determining its biological interactions and efficacy. Overall, this compound exemplifies the complexity and diversity of chemical structures that can be explored for therapeutic purposes.

Formula: C₁₄H₁₇ClN₂O

PNU-282987 S enantiomer free base 

CAS: 737727-12-7

Formula: C₁₄H₁₇ClN₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 264.7506

Ref: IN-DA01EOAV

PNU-282987 S enantiomer free base

CAS: 737727-12-7

PNU-282987 S enantiomer free base

Purity: ≥98%

Molecular weight: 264.75g/mol

Ref: 54-BUP02899

PNU-282987 S enantiomer free base

CAS: 737727-12-7

PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).

Formula: C₁₄H₁₇ClN₂O

Purity: 99.74%

Color and Shape: Solid

Molecular weight: 264.75

Ref: TM-T7695

PNU-282987 S enantiomer free base

CAS: 737727-12-7

PNU-282987 is a novel chemical compound that belongs to the group of ligands. It binds to the alpha subunit of the GABA receptor in the central nervous system, which is responsible for regulating neuronal excitability. PNU-282987 is a potent activator of this receptor, and has been shown to increase the frequency of spontaneous inhibitory postsynaptic currents (sIPSCs) in mouse hippocampal neurons. PNU-282987 has no effect on other ligand-gated ion channels or on the binding of various radioligands to glutamate receptors. It also does not inhibit protein synthesis or DNA replication, nor does it bind to antibodies directed against GABA receptors.

Formula: C₁₄H₁₇ClN₂O

Purity: Min. 95%

Molecular weight: 264.75 g/mol

Ref: 3D-MEB72712