CAS 73816-42-9

Meclocycline sulfosalicylate

Description:

Meclocycline sulfosalicylate is a chemical compound that belongs to the class of tetracycline antibiotics, which are known for their broad-spectrum antibacterial activity. This substance is a derivative of meclocycline, characterized by the presence of a sulfosalicylate moiety that enhances its solubility and bioavailability. It exhibits antibacterial properties by inhibiting protein synthesis in bacteria, making it effective against a variety of gram-positive and gram-negative organisms. Meclocycline sulfosalicylate is typically used in veterinary medicine and may also have applications in treating certain infections in humans. The compound is generally administered orally or parenterally, depending on the formulation. Its pharmacokinetics involve absorption in the gastrointestinal tract, distribution throughout body tissues, and eventual excretion primarily through the kidneys. As with other tetracyclines, it may have side effects, including gastrointestinal disturbances and potential effects on bone and teeth development in children. Proper dosage and administration are crucial to minimize resistance development and ensure therapeutic efficacy.

Formula: C₂₉H₂₇ClN₂O₁₄S

InChI: InChI=1/C22H21ClN2O8.C7H6O6S/c1-6-9-7(23)4-5-8(26)11(9)16(27)12-10(6)17(28)14-15(25(2)3)18(29)13(21(24)32)20(31)22(14,33)19(12)30;8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h4-5,10,14-15,17,26-28,32-33H,1,24H2,2-3H3;1-3,8H,(H,9,10)(H,11,12,13)/b21-13-;/t10-,14-,15+,17+,22+;/m1./s1

InChI key: InChIKey=FYSVKUUNXYGFLA-CCHMMTNSSA-N

SMILES: O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)([C@@H](O)[C@]3(C(=C2O)C(=O)C=4C(C3=C)=C(Cl)C=CC4O)[H])[H].C(O)(=O)C1=CC(S(=O)(=O)O)=CC=C1O

Synonyms:

• (4S,4aR,5S,5aR,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide mono(5-sulfosalicylate) (salt)
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4S,4aR,5S,5aR,12aS)-, mono(2-hydroxy-5-sulfobenzoate) (salt)
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-, mono(2-hydroxy-5-sulfobenzoate) (salt)
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, [4S-(4α,4aα,5α,5aα,12aα)]-, mono(2-hydroxy-5-sulfobenzoate) (salt)
• 2-hydroxy-5-sulfobenzoic acid - (2Z,4S,4aR,5S,5aR,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methylidene-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione (1:1)
• Benzoic acid, 2-hydroxy-5-sulfo-, compd. with (4S,4aR,5S,5aR,12aS)-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide (1:1)
• Benzoic acid, 2-hydroxy-5-sulfo-, compd. with (4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide (1:1)
• Benzoic acid, 2-hydroxy-5-sulfo-, compd. with [4S-(4α,4aα,5α,5aα,12aα)]-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide (1:1)
• Meclan
• Meclan Cream
• Meclocycline 5-sulfosalicylate
• Meclocycline sulfosalicylate [USAN]
• Mecloderm
• Meclosorb
• Meclutin
• Salicylic acid, 5-sulfo-, compd. with 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide
• Traumatociclina
• Unii-46Vza7Rx2B
• Meclocycline sulfosalicylate
• Einecs 277-614-2
• (4S,4aR,5S,12aS)-7-chloro-4-(diMethylaMino)-3,5,10,12,12a-pentahydroxy-6-Methylene-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxaMide 2-hydroxy-5-sulfobenzoate
• FYSVKUUNXYGFLA-CCHMMTNSSA-N
• Meclocycline Sulfosalicylate (300 mg)
• MECLOCYCLINE SULFOSALICYLATE SALT
• MECLOCYLINESULFOSALICYLATE

Meclocycline sulfosalicylate salt

CAS: 73816-42-9

Formula: C₂₉H₂₇ClN₂O₁₄S

Purity: 95%

Color and Shape: Solid

Molecular weight: 695.0477

Ref: IN-DA008Q0H

Meclocycline sulfosalicylate salt

CAS: 73816-42-9

Meclocycline sulfosalicylate salt (Mecloderm) is a tetracycline antibiotic with broad-spectrum antimicrobial activity that prevents bacterial skin infections.

Formula: C₂₂H₂₁ClN₂O₈·C₇H₆O₆S

Purity: 95.53% - 99.07%

Color and Shape: Crystals

Molecular weight: 695.05

Ref: TM-T0281

Meclocycline sulfosalicylate salt

CAS: 73816-42-9

Formula: C₂₂H₂₁ClN₂O₈·C₇H₆O₆S

Molecular weight: 695.05

Ref: 7W-GA5097

Meclocycline sulfosalicylate salt

CAS: 73816-42-9

Meclocycline sulfosalicylate salt

Purity: ≥95%

Molecular weight: 695.05g/mol

Ref: 54-BUP06877

Meclocycline Sulfosalicylate Salt

CAS: 73816-42-9

Meclocycline Sulfosalicylate Salt

Purity: 98%

Molecular weight: 695.05g/mol

Ref: 54-OR1023143

Meclocycline Sulfosalicylate Salt

Controlled Product

CAS: 73816-42-9

Stability Hygroscopic
Applications Meclocycline is a tetracycline antibiotic that is topically used for skin infections and irritations.
References Gohil, V.M., et al.: Nature. Biotechol., 28, 249 (2010); Paemen, L., et al.: Biochem. Pharmacol., 52, 105 (1996);

Formula: C₂₂H₂₁ClN₂O₈·C₇H₆O₆S

Color and Shape: Neat

Molecular weight: 695.05

Ref: TR-M202720

Meclocycline sulfosalicylate

CAS: 73816-42-9

Meclocycline sulfosalicylate salt is a research chemical with various characteristics and applications. It is commonly used in laboratory settings for its unique properties. Meclocycline sulfosalicylate salt has been found to have bioavailability advantages, making it an ideal compound for certain experiments and studies. Additionally, it has been shown to interact with various substances such as zolmitriptan, glycidyl methacrylate, benzoate, trifluoromethanesulfonate, interferon, adenine, aldehyde, cellulose, inositol, strontium chloride, and fatty acids. These interactions may contribute to its efficacy in specific research contexts. Overall, meclocycline sulfosalicylate salt is a valuable tool for scientists and researchers looking to explore different areas of study.

Formula: C₂₂H₂₁ClN₂O₈•C₇H₆O₆S

Purity: Min. 95%

Molecular weight: 695.05 g/mol

Ref: 3D-YCA81642

Meclocycline Sulfosalicylate

CAS: 73816-42-9

Formula: C₂₂H₂₁ClN₂O₈C₇H₆O₆S

Molecular weight: 476.87 : 218.18

Ref: ST-EA-CP-M120001

Meclocycline Sulfosalicylate (DISCONTINUED)

CAS: 73816-42-9

Tetracyclines and their derivatives; salts thereof

Formula: C₂₂H₂₁ClN₂O₈·C₇H₆O₆S

Color and Shape: Light Yellow Powder

Molecular weight: 694.08715

Ref: 45-1377508