CAS 73819-26-8

2,5-Bis(4-amidinophenyl)furan

Description:

2,5-Bis(4-amidinophenyl)furan, identified by its CAS number 73819-26-8, is a synthetic organic compound characterized by its furan core substituted with two 4-amidinophenyl groups. This compound typically exhibits properties associated with both furan derivatives and amidine functionalities, which may contribute to its biological activity. The presence of the amidine groups suggests potential for strong hydrogen bonding and interactions with biological targets, making it of interest in medicinal chemistry. The furan ring provides a degree of aromaticity and stability, while also allowing for potential reactivity in various chemical reactions. In terms of solubility, compounds of this nature may be soluble in organic solvents but less so in water, depending on the specific substituents and their interactions. Overall, 2,5-Bis(4-amidinophenyl)furan is notable for its potential applications in pharmaceuticals and research, particularly in areas related to its biological activity and chemical reactivity.

Formula: C₁₈H₁₆N₄O

InChI: InChI=1S/C18H16N4O/c19-17(20)13-5-1-11(2-6-13)15-9-10-16(23-15)12-3-7-14(8-4-12)18(21)22/h1-10H,(H3,19,20)(H3,21,22)

InChI key: InChIKey=ZJHZBDRZEZEDGB-UHFFFAOYSA-N

SMILES: C(=N)(N)C1=CC=C(C=2OC(=CC2)C3=CC=C(C(=N)N)C=C3)C=C1

Synonyms:

• 2,5-Bis(4-amidinophenyl)furan
• 2,5-Bis(4-guanylphenyl)furan
• 4,4'-Furan-2,5-Diyldibenzenecarboximidamide
• 4,4′-(2,5-Furandiyl)bis[benzenecarboximidamide]
• Benzenecarboximidamide, 4,4′-(2,5-furandiyl)bis-
• Db-075
• Db-75
• Furamidine
• NSC 305831

Furamidine

CAS: 73819-26-8

Furamidine is a PRMT1-selective, cell-permeable inhibitor (IC50: 9.4μM), also targeting TDP-1, and is an antiparasitic bisbenzamidine derivative.

Formula: C₁₈H₁₆N₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 304.35

Ref: TM-T11338