CAS 73836-78-9

Leukotriene D4

Description:

Leukotriene D4 (LTD4) is a potent lipid mediator that plays a significant role in inflammatory responses and various physiological processes. It is a member of the leukotriene family, which are derived from arachidonic acid through the lipoxygenase pathway. LTD4 is characterized by its involvement in bronchoconstriction, increased vascular permeability, and modulation of immune responses, making it particularly relevant in conditions such as asthma and allergic reactions. The substance is known for its ability to bind to specific leukotriene receptors, leading to various biological effects, including smooth muscle contraction and chemotaxis of immune cells. LTD4 is typically synthesized and released by immune cells, such as mast cells and eosinophils, during inflammatory processes. Its structure includes a conjugated triene system, which is crucial for its biological activity. Due to its significant role in pathophysiological conditions, LTD4 is a target for therapeutic interventions aimed at managing asthma and other allergic diseases.

Formula: C₂₅H₄₀N₂O₆S

InChI: InChI=1S/C25H40N2O6S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22(21(28)15-14-17-23(29)30)34-19-20(26)25(33)27-18-24(31)32/h6-7,9-13,16,20-22,28H,2-5,8,14-15,17-19,26H2,1H3,(H,27,33)(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t20-,21-,22+/m0/s1

InChI key: InChIKey=YEESKJGWJFYOOK-IJHYULJSSA-N

SMILES: [C@H](SC[C@@H](C(NCC(O)=O)=O)N)([C@H](CCCC(O)=O)O)/C=C/C=C/C=C\C/C=C\CCCCC

Synonyms:

• Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))-
• Glycine, N-[S-[1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl]-<span class="text-smallcaps">L</span>-cysteinyl]-, [R-[R*,S*-(E,E,Z,Z)]]-
• Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-<span class="text-smallcaps">L</span>-cysteinyl-
• Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]-<span class="text-smallcaps">L</span>-cysteinyl-
• LTD (sub 4)
• LTD₄
• Leukotriene D
• Leukotriene D(sub 4)
• Leukotriene D₄
• S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-<span class="text-smallcaps">L</span>-cysteinylglycine
• S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteinylglycine
• S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}cysteinylglycine
• Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl-
• S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinylglycine
• Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-

Leukotriene D4

CAS: 73836-78-9

Leukotriene D4

Purity: ≥98%

Molecular weight: 496.66g/mol

Ref: 54-BUP21662

Leukotriene D4

CAS: 73836-78-9

Formula: C₂₅H₄₀N₂O₆S

Purity: ≥ 95%

Color and Shape: Liquid

Molecular weight: 496.66

Ref: 7W-GL9997

Leukotriene D4

CAS: 73836-78-9

Formula: C₂₅H₄₀N₂O₆S

Molecular weight: 496.66

Ref: 4Z-L-171004

Leukotriene D4

CAS: 73836-78-9

Leukotriene D4 (LTD4) is a potent pro-inflammatory mediator formed from arachidonic acid, a bronchoconstrictor, and induces osteoclast senescence.

Formula: C₂₅H₄₀N₂O₆S

Purity: 98.50%

Color and Shape: Solid

Molecular weight: 496.66

Ref: TM-T38128

LTD4 (Leukotriene D4)

Controlled Product

CAS: 73836-78-9

Formula: C₂₅H₄₀N₂O₆S

Color and Shape: Neat

Molecular weight: 496.66

Ref: TR-L473493

Leukotriene d4

CAS: 73836-78-9

Leukotriene D4 is an inhibitor analog that has been found in human urine. It has been studied for its potential as an anticancer agent due to its ability to induce apoptosis in cancer cells. Leukotriene D4 also inhibits protein kinases, which are enzymes involved in cell growth and division. Medicinal research has shown that this compound may have potential as a therapeutic agent for the treatment of cancer and other diseases. In Chinese medicine, Leukotriene D4 is used as an inhibitor of tumor growth and proliferation. Researchers are continuing to study the effects of this compound on various types of cancer cells to determine its full potential as a medicinal agent.

Formula: C₂₅H₄₀N₂O₆S

Purity: Min. 95%

Molecular weight: 496.7 g/mol

Ref: 3D-YCA83678