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CAS 73865-18-6

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Nardeterol

Description:
Nardeterol is a long-acting beta-2 adrenergic agonist (LABA) primarily used in the management of chronic obstructive pulmonary disease (COPD) and asthma. As a selective agonist, it works by stimulating beta-2 adrenergic receptors in the smooth muscle of the airways, leading to bronchodilation and improved airflow. Nardeterol is characterized by its prolonged duration of action, which allows for once-daily dosing, enhancing patient compliance. The substance is typically administered via inhalation, ensuring targeted delivery to the lungs. Its chemical structure includes a naphthalene ring, contributing to its pharmacological properties. Nardeterol is often combined with other medications, such as corticosteroids, to provide comprehensive management of respiratory conditions. Safety and efficacy profiles have been established through clinical trials, highlighting its role in improving lung function and reducing exacerbations in patients with obstructive airway diseases. As with any medication, potential side effects may include cardiovascular effects, tremors, and hypokalemia, necessitating careful monitoring during treatment.
Formula:C20H24FN3O2
InChI:InChI=1/C20H24FN3O2/c1-20(2,9-10-24-13-22-17-5-3-4-6-18(17)24)23-12-19(26)15-8-7-14(25)11-16(15)21/h3-8,11,13,19,23,25-26H,9-10,12H2,1-2H3
Synonyms:
  • (+-)-alpha-(((3-(1-Benzimidazolyl)-1,1-dimethylpropyl)amino)methyl)-2-fluoro-4-hydroxybenzyl alcohol
  • Nardeterolum
  • Som 1122
  • Nardeterolum [INN-Latin]
  • Nardeterol [INN]
  • UNII-70859437W3
  • 4-(2-{[4-(1H-benzimidazol-1-yl)-2-methylbutan-2-yl]amino}-1-hydroxyethyl)-3-fluorophenol
  • Benzenemethanol, alpha-(((3-(1H-benzimidazol-1-yl)-1,1-dimethylpropyl)amino)methyl)-2-fluoro-4-hydroxy-
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