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CAS 739-71-9

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Trimipramine

Description:
Trimipramine is a tricyclic antidepressant (TCA) primarily used in the treatment of major depressive disorder and certain anxiety disorders. It functions by inhibiting the reuptake of neurotransmitters, particularly norepinephrine and serotonin, thereby enhancing mood and alleviating depressive symptoms. Trimipramine is characterized by its relatively low sedative effects compared to other TCAs, making it a preferred option for some patients. The compound has a complex chemical structure, featuring a three-ring system that contributes to its pharmacological activity. It is typically administered orally and is metabolized in the liver, with a half-life that allows for once-daily dosing in many cases. Common side effects may include dry mouth, constipation, and drowsiness, which are typical of many tricyclic antidepressants. Due to its potential for interactions with other medications and its side effect profile, careful monitoring is recommended during treatment. Trimipramine's efficacy and safety profile make it a valuable option in the management of depression, particularly for patients who may not respond to other classes of antidepressants.
Formula:C20H26N2
InChI:InChI=1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3
InChI key:InChIKey=ZSCDBOWYZJWBIY-UHFFFAOYSA-N
SMILES:C(C(CN(C)C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2
Synonyms:
  • (.+-.)-Trimipramine
  • 10,11-Dihydro-5-(3-dimethylamino-2-methylpropyl)-5H-dibenz[b,f]azepine
  • 10,11-Dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamine
  • 5-(γ-Dimethylamino-β-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine
  • 5-[3-(Dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine
  • 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-
  • 7162 Rp
  • Il 6001
  • Rhotrimine
  • Rp 7162
  • See more synonyms
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