CAS 73971-82-1

2,4(1H,3H)-Pyrimidinedione,1-(3-azido-2,3-dideoxy-b-D-threo-pentofuranosyl)-5-methyl-

Description:

2,4(1H,3H)-Pyrimidinedione, 1-(3-azido-2,3-dideoxy-b-D-threo-pentofuranosyl)-5-methyl- is a synthetic nucleoside analog that features a pyrimidine ring structure with a methyl group and an azido group attached to a sugar moiety. This compound is characterized by its potential antiviral properties, particularly in the context of inhibiting viral replication. The azido group is significant for its role in bioorthogonal chemistry, allowing for selective reactions in biological systems. The presence of the dideoxyribose sugar enhances its stability and resistance to nucleases, making it a candidate for therapeutic applications. The compound's structure suggests it may interact with nucleic acids, potentially interfering with viral RNA or DNA synthesis. Its unique combination of functional groups contributes to its biological activity, making it a subject of interest in medicinal chemistry and drug development. As with many nucleoside analogs, further studies are necessary to fully understand its pharmacokinetics, efficacy, and safety profile.

Formula: C₁₀H₁₃N₅O₄

Synonyms:

• 1-[(2R,4R,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione
• Zidovudine Impurity 14
• 3'-beta-Azido-3'-deoxy thyMidine
• 3’-beta-Azido-3’-deoxy thymidine AZT(threo), HIV-1 replication inhibitor, Zidovudine’s related substance
• 3'-epi-Azido-3'-deoxythyMidine
• 1-(3-Azido-2,3-dideoxy-beta-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
• AZT(threo), AzddXyloT
• 1-(3-beta-Azido-2,3-dideoxy-beta-D-threopenta-furanosyl)thyMine
• 3’-β-Azido-3’-deoxy thymidine
• Zidovudine Impurity 4

3-epi-Azido-3-deoxythymidine

CAS: 73971-82-1

3’-N-modified nucleoside; Azido-nucleoside

Formula: C₁₀H₁₃N₅O₄

Color and Shape: Solid

Molecular weight: 267.24

Ref: TM-TNU0789

Zidovudine Impurity 4

CAS: 73971-82-1

Formula: C₁₀H₁₃N₅O₄

Molecular weight: 267.25

Ref: 4Z-Z-0814

3'-epi-Azido-3'-deoxythymidine

Controlled Product

CAS: 73971-82-1

Formula: C₁₀H₁₃N₅O₄

Color and Shape: Neat

Molecular weight: 267.241

Ref: TR-A825055

3’-epi-Azido-3’-deoxythymidine-d3

Controlled Product

CAS: 73971-82-1

Formula: C₁₀D₃H₁₀N₅O₄

Color and Shape: Neat

Molecular weight: 270.26

Ref: TR-A825057

1-(3-β-azido-2,3-dideoxy-β-D-threopentafuranosyl)thymine

CAS: 73971-82-1

1-(3-Beta-azido-2,3-dideoxy-beta-D-threopentafuranosyl)thymine is an inhibitor of ion channels. It is a ligand that binds to the beta subunit of voltage-gated potassium channels and blocks the opening of these channels. The binding site for 1-(3-Beta-azido-2,3-dideoxy-beta-D-threopentafuranosyl)thymine has been identified as being located in the selectivity filter region at the extracellular side of the channel. This compound has shown to be a potent inhibitor of ion channels with IC50s in the low nanomolar range.

Formula: C₁₀H₁₃N₅O₄

Purity: Min. 95%

Molecular weight: 267.24 g/mol

Ref: 3D-YCA97182