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CAS 74011-42-0

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Oxonorfloxacin

Description:
Oxonorfloxacin is a synthetic fluoroquinolone antibiotic that exhibits broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. The compound is characterized by its bicyclic core structure, which includes a fluorine atom that enhances its potency and spectrum of activity against Gram-positive and Gram-negative bacteria. Oxonorfloxacin is typically administered orally and is known for its favorable pharmacokinetic properties, including good absorption and distribution in body tissues. Its efficacy is often evaluated against a range of pathogens, including those resistant to other antibiotics. However, like other fluoroquinolones, it may be associated with side effects such as gastrointestinal disturbances, central nervous system effects, and potential tendon damage. As with any antibiotic, appropriate use is crucial to minimize the development of resistance. Overall, Oxonorfloxacin represents a valuable option in the arsenal of antimicrobial agents, particularly in the context of treating infections caused by resistant bacterial strains.
Formula:C16H16FN3O4
InChI:InChI=1S/C16H16FN3O4/c1-2-19-7-10(16(23)24)15(22)9-5-11(17)13(6-12(9)19)20-4-3-18-14(21)8-20/h5-7H,2-4,8H2,1H3,(H,18,21)(H,23,24)
InChI key:InChIKey=OIOFPHGTOUDKAJ-UHFFFAOYSA-N
SMILES:C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2)N3CC(=O)NCC3
Synonyms:
  • 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(3-oxo-1-piperazinyl)-3-quinolinecarboxylic acid
  • 3-Quinolinecarboxylic Acid, 1-Ethyl-6-Fluoro-1,4-Dihydro-4-Oxo-7-(3-Oxo-1-Piperazinyl)-
  • 4-Oxo-norfloxacin
  • Oxonorfloxacin
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