CAS 74011-56-6

N-Acetylnorfloxacin

Description:

N-Acetylnorfloxacin is a synthetic antibacterial agent belonging to the fluoroquinolone class of antibiotics. It is characterized by its broad-spectrum activity against various Gram-positive and Gram-negative bacteria, making it effective in treating a range of infections. The chemical structure of N-Acetylnorfloxacin includes a bicyclic core with a fluorine atom, which enhances its antibacterial potency by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. This compound is typically administered orally and is known for its favorable pharmacokinetic properties, including good absorption and distribution in body tissues. N-Acetylnorfloxacin is also associated with a relatively low incidence of side effects, although, like other fluoroquinolones, it may pose risks such as tendonitis or tendon rupture in certain populations. Its use is subject to regulatory approval and guidelines, and it is important to consider bacterial resistance patterns when prescribing this antibiotic. Overall, N-Acetylnorfloxacin represents a valuable option in the arsenal against bacterial infections.

Formula: C₁₈H₂₀FN₃O₄

InChI: InChI=1S/C18H20FN3O4/c1-3-20-10-13(18(25)26)17(24)12-8-14(19)16(9-15(12)20)22-6-4-21(5-7-22)11(2)23/h8-10H,3-7H2,1-2H3,(H,25,26)

InChI key: InChIKey=HBULVPCEMFKAOE-UHFFFAOYSA-N

SMILES: C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2)N3CCN(C(C)=O)CC3

Synonyms:

• 3-Quinolinecarboxylic Acid, 7-(4-Acetyl-1-Piperazinyl)-1-Ethyl-6-Fluoro-1,4-Dihydro-4-Oxo-
• 7-(4-Acetyl-1-piperazinyl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
• N-Acetylnorfloxacin

7-(4-Acetylpiperazin-1-Yl)-1-Ethyl-6-Fluoro-4-Oxoquinoline-3-Carboxylate

CAS: 74011-56-6

7-(4-Acetylpiperazin-1-Yl)-1-Ethyl-6-Fluoro-4-Oxoquinoline-3-Carboxylate is a fluoroquinolone antibiotic that inhibits the bacterial enzyme DNA gyrase. It is used for wastewater treatment and gene sequence analysis. 7-(4-Acetylpiperazin-1-Yl)-1-Ethyl-6-Fluoro-4 -Oxoquinoline 3 Carboxylate has been shown to inhibit synthetase and expressed genes in bacteria, as well as chemical processes such as proton exchange. This drug also has antimicrobial properties against a wide range of other microorganisms, including enterobacter, which is found in the human gastrointestinal tract. 7-(4 Acetylpiperazin 1 Yl) -1 Ethyl 6 Fluoro 4 Oxoquinoline 3 Carboxylic Acid

Formula: C₁₈H₁₉FN₃O₄

Purity: Min. 95%

Molecular weight: 360.36 g/mol

Ref: 3D-FA99312