CymitQuimica logo

CAS 74014-51-0

:

Rokitamycin

Description:
Rokitamycin is a macrolide antibiotic that is derived from the fermentation of the bacterium Streptomyces griseus. It is characterized by its large lactone ring structure, which is typical of macrolides, and it possesses a unique side chain that contributes to its biological activity. Rokitamycin exhibits antibacterial properties, particularly against Gram-positive bacteria, and is known for its effectiveness in treating respiratory tract infections and other bacterial diseases. The compound functions by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of bacteria. In addition to its antibacterial activity, Rokitamycin has been studied for its potential immunomodulatory effects. Its pharmacokinetics include good oral bioavailability and a relatively long half-life, allowing for convenient dosing regimens. However, like other antibiotics, it may have side effects and can lead to antibiotic resistance if misused. Overall, Rokitamycin represents an important class of antibiotics with specific applications in clinical settings.
Formula:C42H69NO15
InChI:InChI=1S/C42H69NO15/c1-11-16-32(48)55-40-27(6)53-34(23-42(40,7)58-31(47)12-2)56-37-26(5)54-41(36(50)35(37)43(8)9)57-38-28(19-20-44)21-24(3)29(45)18-15-13-14-17-25(4)52-33(49)22-30(46)39(38)51-10/h13-15,18,20,24-30,34-41,45-46,50H,11-12,16-17,19,21-23H2,1-10H3/b14-13+,18-15+/t24-,25-,26-,27+,28+,29+,30-,34+,35-,36-,37-,38+,39+,40+,41+,42-/m1/s1
InChI key:InChIKey=VYWWNRMSAPEJLS-MDWYKHENSA-N
SMILES:O([C@H]1[C@@H](CC=O)C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@@H](C)OC(=O)C[C@@H](O)[C@@H]1OC)[C@H]2[C@H](O)[C@@H](N(C)C)[C@H](O[C@H]3C[C@](OC(CC)=O)(C)[C@@H](OC(CCC)=O)[C@H](C)O3)[C@@H](C)O2
Synonyms:
  • CCRIS 5267
  • Ricamycin
  • Rokitamicina
  • TMS 19Q
  • 3′′-Propionylleucomycin A5
  • Ricamycin
  • Rokitamycinum
  • 3"-O-Propionylleucomycin A5
  • (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl]oxy}-2,4-dimethyl-4-(propanoyloxy)tetrahydro-2H-pyran-3-yl butanoate (non-preferred name)
  • TMS 19Q
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.