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CAS 74046-07-4

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(S)-Vigabatrin

Description:
(S)-Vigabatrin is a pharmaceutical compound primarily used as an anticonvulsant in the treatment of epilepsy, particularly for patients who do not respond to other medications. It is a derivative of gamma-aminobutyric acid (GABA) and functions as an irreversible inhibitor of the enzyme GABA transaminase, leading to increased levels of GABA in the brain, which helps to stabilize neuronal activity. The compound is characterized by its chiral nature, with the (S)-enantiomer being the active form responsible for its therapeutic effects. In terms of physical properties, (S)-Vigabatrin is typically a white to off-white crystalline powder, soluble in water, and has a specific melting point range. Its chemical structure includes a cyclopropane ring, contributing to its unique pharmacological profile. While effective, it is important to monitor for potential side effects, including visual field defects, and it is contraindicated in certain populations. Overall, (S)-Vigabatrin represents a significant advancement in the management of refractory epilepsy.
Formula:C6H11NO2
InChI:InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m1/s1
InChI key:InChIKey=PJDFLNIOAUIZSL-RXMQYKEDSA-N
SMILES:[C@H](CCC(O)=O)(C=C)N
Synonyms:
  • (+)-γ-Vinyl GABA
  • (4S)-4-Amino-5-hexenoic acid
  • (S)-(+)-Gamma-vinyl-GABA
  • (S)-4-Amino-5-hexenoic acid
  • (S)-Vigabatrin
  • 4(S)-Amino-5-hexenoic acid
  • 5-Hexenoic acid, 4-amino-, (4S)-
  • 5-Hexenoic acid, 4-amino-, (S)-
  • Rmi 71890
  • (4S)-4-Aminohex-5-enoic acid
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Found 3 products.
  • S(+)-4-AMINOHEXENOIC ACID
    Indagoo
    + Info

    S(+)-4-AMINOHEXENOIC ACID

    CAS:
    Formula:C6H11NO2
    Purity:95%
    Color and Shape:Solid
    Molecular weight:129.1570

    Ref: IN-DA00FDS4

    100mg
    To inquire
    250mg
    To inquire
  • S(+)-γ-Vinyl-GABA
    Fluorochem
    + Info

    S(+)-γ-Vinyl-GABA

    CAS:
    Formula:C6H11NO2
    Purity:95%
    Molecular weight:129.159

    Ref: 10-M02662

    250mg
    1,070.00€
  • (S)-Vigabatrin
    TRC
    + Info

    (S)-Vigabatrin

    Controlled Product
    CAS:
    <p>Applications Vigabatrin is a novel anti-epileptic drug. Antidepressant; antipsychotic; anxiolytic.<br>References Vajda, F., et al.: Clin. Neurosci., 7, 88 (2000), Beghi, E., et al.: Lancet. Neurol., 3, 618 (2004), Sagirli, O., et al.: J. Pharmaceut. Biomed., 42, 618 (2006),<br></p>
    Formula:C6H11NO2
    Color and Shape:Neat
    Molecular weight:129.16

    Ref: TR-V253000

    25mg
    1,601.00€
    2500µg
    220.00€