CAS 74075-34-6

Vinorelbine N'b-Oxide Sulfate Salt

Description:

Vinorelbine N'b-Oxide Sulfate Salt, with the CAS number 74075-34-6, is a derivative of vinorelbine, a vinca alkaloid used primarily in cancer chemotherapy. This compound exhibits antitumor activity by inhibiting microtubule formation, thereby disrupting mitosis in cancer cells. The N'b-oxide modification enhances its pharmacological properties, potentially improving its efficacy and reducing toxicity compared to its parent compound. As a sulfate salt, it is typically more soluble in aqueous solutions, facilitating its administration in clinical settings. The compound is characterized by its specific molecular structure, which includes a complex arrangement of carbon, hydrogen, nitrogen, and oxygen atoms. Its stability, solubility, and bioavailability are critical factors influencing its therapeutic application. Vinorelbine N'b-Oxide Sulfate Salt is primarily utilized in the treatment of various malignancies, including non-small cell lung cancer and breast cancer, and is often administered intravenously. As with many chemotherapeutic agents, careful monitoring of side effects and patient response is essential during treatment.

Formula: C₄₅H₅₄N₄O₉

Synonyms:

• Vinorelbine EP Impurity D/6 '-N-Oxide vinorelbine
• Vinorelbine N'b-Oxide
• Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2-oxido-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-
• Vinorelbine EP Impurity D/Vinorelbine N'b-Oxide
• Vinorelbine EP Impurity D/6 '-N-Oxide Vinorelbine/(2β,3β,4β,5α,12R,19α)-4-(acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2-oxido-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-Aspidosperm
• Vinorelbine N-Oxide Sulfate
• Vinorelbine Impurity 4（Vinorelbine EP Impurity D）
• Vinorelbine N'b-Oxide Sulfate Salt

Vinorelbine EP Impurity D

CAS: 74075-34-6

Formula: C₄₅H₅₄N₄O₉

Molecular weight: 794.95

Ref: 4Z-V-040003

Vinorelbine N'b-Oxide

Controlled Product

CAS: 74075-34-6

Applications An analog of Vinorelbine Ditartrate (V315000), an antineoplastic.
References Mathe, G., et al.: Cancer Letters, 27, 285 (1985), Levegue, D., et al.: Clin. Pharmacokinet., 31, 184 (1996), Curran, M.P., et al.: Drugs Aging., 19, 695 (2002),

Formula: C₄₅H₅₄N₄O₉

Color and Shape: Neat

Molecular weight: 794.93

Ref: TR-V315100

Vinorelbine N'B-oxide

CAS: 74075-34-6

Vinorelbine N'B-oxide is a drug product that is used as an analytical or impurity standard. It is a natural product and its chemical structure has been determined by HPLC. Vinorelbine N'B-oxide is metabolized in vivo to vinorelbine and N'-desmethylvinorelbine, which are metabolites of vinorelbine. It has been shown to be useful for metabolism studies.

Formula: C₄₅H₅₄N₄O₉

Purity: Min. 95%

Molecular weight: 794.93 g/mol

Ref: 3D-ZCA07534

Vinorelbine EP Impurity D

CAS: 74075-34-6

Formula: C₄₅H₅₄N₄O₉

Molecular weight: 794.95

Ref: ST-EA-CP-V49008