CAS 74103-06-3

Ketorolac

Description:

Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for its analgesic properties, particularly in managing moderate to severe pain. It is characterized by its ability to inhibit the enzyme cyclooxygenase (COX), which plays a crucial role in the synthesis of prostaglandins, compounds involved in inflammation and pain signaling. Ketorolac is often administered via oral, intramuscular, or intravenous routes, and is known for its rapid onset of action. The substance is typically utilized in postoperative settings or for acute pain relief, but its use is generally limited to short-term treatment due to potential side effects, including gastrointestinal bleeding, renal impairment, and cardiovascular risks. Ketorolac is also notable for its relatively high potency compared to other NSAIDs, making it effective in lower doses. As with all medications, it is essential to use Ketorolac under medical supervision to mitigate risks and monitor for adverse effects.

Formula: C₁₅H₁₃NO₃

InChI: InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)

InChI key: InChIKey=OZWKMVRBQXNZKK-UHFFFAOYSA-N

SMILES: C(=O)(C=1N2C(C(C(O)=O)CC2)=CC1)C3=CC=CC=C3

Synonyms:

• 1H-pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-
• 5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
• 5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
• Aagn 199584
• Acular LS
• Keromin
• Rs 37619
• Sprix
• Sukerin
• acide 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylique
• Ketorolac

Ketorolac

CAS: 74103-06-3

Formula: C₁₅H₁₃NO₃

Color and Shape: Off-White Solid

Molecular weight: 255.28

Ref: 4Z-K-0313

Ketorolac

CAS: 74103-06-3

Ketorolac

Purity: ≥98%

Molecular weight: 255.27g/mol

Ref: 54-BUP17317

Ketorolac

Controlled Product

CAS: 74103-06-3

Formula: C₁₅H₁₃NO₃

Color and Shape: Off White Solid

Molecular weight: 255.27

Ref: 04-C14533000

Ketorolac Tromethamine

CAS: 74103-06-3, 74103-07-4

Formula: C₁₅H₁₃NO₃·C₄H₁₁NO₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 376.41

Ref: 3B-K0053

Ketorolac

CAS: 74103-06-3

Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.

Formula: C₁₅H₁₃NO₃

Purity: 99.68%

Color and Shape: White Crystalline Or White Powder

Molecular weight: 255.27

Ref: TM-T21412

5-Benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylic acid

CAS: 74103-06-3

5-Benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylic acid

Formula: C₁₅H₁₃NO₃

Purity: 95%

Color and Shape: light yellow powder

Molecular weight: 255.27g/mol

Ref: 54-OR345134

rac Ketorolac

Controlled Product

CAS: 74103-06-3

Applications Ketorolac is an analgesic; anti-inflammatory.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Etman, M., et al.: Pharm. Technol., 32, 58 (2008), Chelladurai, S., et al.: Chem. Pharm. Bull., 56, 1596 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),

Formula: C₁₅H₁₃NO₃

Color and Shape: Off White Solid

Molecular weight: 255.27

Ref: TR-K235615

5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

CAS: 74103-06-3

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 255.2729949951172

Ref: 10-F242512

Ketorolac

CAS: 74103-06-3

Ketorolac is a nonsteroidal anti-inflammatory drug that acts by inhibiting the synthesis of prostaglandins. It is used to control moderate to severe pain, and for reducing postoperative, postpartum and other types of pain. Ketorolac has been shown to be effective in a variety of clinical settings, including those involving hepatic impairment and congestive heart failure. The drug has minimal toxicity and can be used at high doses without adverse effects on the liver or kidney. In addition, ketorolac does not produce significant changes in pge2 levels in experimental models or human serum when administered orally.

Formula: C₁₅H₁₃NO₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 255.27 g/mol

Ref: 3D-FK35139

5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic

CAS: 74103-06-3

5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic (5BPC) is a drug that is used for the treatment of pain. It has been shown to be safe and effective in treating postoperative pain when given by intravenous infusion or as an oral tablet. 5BPC has minimal toxicity and is metabolized primarily by the liver with a half life of 2.6 hours. The drug has been found to have pharmacokinetic properties that allow it to be used safely in patients with hepatic impairment and in those recovering from abdominal surgery. 5BPC is a prodrug that undergoes biotransformation by esterases into its active form, pyrrolizidine alkaloid (PA). PA acts as a nonsteroidal anti-inflammatory agent and inhibits prostaglandin synthesis, which leads to analgesia. This drug also has minimal drug interactions because

Formula: C₁₅H₁₃O₃N

Purity: Min. 95%

Molecular weight: 255.27 g/mol

Ref: 3D-IB58062