CymitQuimica logo

CAS 74103-07-4

:

Ketorolac tromethamine

Description:
Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for its analgesic properties, particularly in the management of moderate to severe pain. It is characterized by its ability to inhibit the enzyme cyclooxygenase (COX), leading to a decrease in the synthesis of prostaglandins, which are mediators of inflammation and pain. This compound is typically administered via oral, intramuscular, or intravenous routes and is known for its rapid onset of action. Ketorolac tromethamine is often utilized in postoperative settings and for short-term pain relief due to its potent analgesic effects. However, it is important to note that prolonged use can lead to adverse effects, including gastrointestinal bleeding, renal impairment, and cardiovascular risks. The substance is soluble in water, which facilitates its formulation in various dosage forms. As with all medications, it should be used under medical supervision, and patients should be monitored for potential side effects.
Formula:C15H13NO3·C4H11NO3
InChI:InChI=1S/C15H13NO3.C4H11NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13;5-4(1-6,2-7)3-8/h1-7,11H,8-9H2,(H,18,19);6-8H,1-3,5H2
InChI key:InChIKey=BWHLPLXXIDYSNW-UHFFFAOYSA-N
SMILES:C(=O)(C=1N2C(C(C(O)=O)CC2)=CC1)C3=CC=CC=C3.C(CO)(CO)(CO)N
Synonyms:
  • (+/-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris(hydroxymethyl)methylamine salt
  • 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, (±)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate (1:1) (salt)
  • 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate (1:1) (salt)
  • 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (±)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
  • 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid-2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)
  • Acular
  • Acular PF
  • Acuvail
  • Dolac
  • Isv 304
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 18 products.