CAS 74115-01-8

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-, hydrobromide (1:1)

Description:

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-, hydrobromide (1:1), with CAS number 74115-01-8, is a chemical compound characterized by its complex bicyclic structure, which includes a benzazepine core. This compound features multiple functional groups, including hydroxyl (-OH) groups and a chloro substituent, which contribute to its reactivity and potential biological activity. The presence of a phenyl group and a propenyl side chain suggests that it may exhibit interesting pharmacological properties, possibly influencing its interaction with biological targets. As a hydrobromide salt, it is likely to be more soluble in water compared to its free base form, which can enhance its bioavailability in pharmaceutical applications. The compound's structural features may also suggest potential uses in medicinal chemistry, particularly in the development of therapeutic agents. However, specific biological activities, toxicity, and detailed applications would require further investigation through empirical studies and literature review.

Formula: C₁₉H₂₀ClNO₂·BrH

InChI: InChI=1S/C19H20ClNO2.BrH/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13;/h2-7,11,16,22-23H,1,8-10,12H2;1H

InChI key: InChIKey=WLXGFAVTAAQOFH-UHFFFAOYSA-N

SMILES: ClC1=C2C(C(CN(CC=C)CC2)C3=CC=CC=C3)=CC(O)=C1O.Br

Synonyms:

• 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-, hydrobromide
• SKF 82598
• 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-, hydrobromide (1:1)
• SKF 82958 HBr
• SKF 82958 hydrobromide

SKF 82958 (hydrobromide)

CAS: 74115-01-8

Formula: C₁₉H₂₁BrClNO₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 410.7325

Ref: IN-DA00FC1U

SKF-82958 hydrobromide

CAS: 74115-01-8

SKF-82958 hydrobromide is a D1/D5 receptor full agonist.

Formula: C₁₉H₂₁BrClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 410.73

Ref: TM-T16892

(+/-)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine HBr

CAS: 74115-01-8

(+/-)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine HBr is a model system for Parkinson's disease that has been shown to have similar effects on locomotor activity as the dopamine antagonist haloperidol. The drug enhances dopaminergic and cholinergic transmission in the brain by binding to kappa opioid receptors. This leads to an increased release of dopamine and acetylcholine that can be blocked by drugs such as naloxone and atropine respectively. (+/-)-6-Chloro-7,8-dihydroxy 3-(allyl)-1-(phenyl) 2,3,4,5 tetrahydro 1H 3 benzazepine HBr has been shown to decrease camp levels in the caudate putamen region of rats

Formula: C₁₉H₂₀ClNO₂·HBr

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 410.73 g/mol

Ref: 3D-FC75160