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CAS 741253-05-4

:

Indole-3-boronic acid

Description:
Indole-3-boronic acid is an organic compound characterized by its boronic acid functional group attached to an indole structure. It typically appears as a white to off-white solid and is soluble in polar solvents such as water and alcohols. This compound is notable for its ability to form reversible covalent bonds with diols, making it useful in various applications, including medicinal chemistry and materials science. Indole-3-boronic acid is often employed in the synthesis of biologically active molecules and as a building block in the development of pharmaceuticals. Its reactivity is influenced by the presence of the boron atom, which can participate in cross-coupling reactions, particularly in the context of Suzuki-Miyaura coupling, a widely used method for forming carbon-carbon bonds. Additionally, the indole moiety contributes to its biological activity, as indole derivatives are known for their roles in neurotransmission and as precursors to various natural products. Overall, indole-3-boronic acid is a versatile compound with significant relevance in both synthetic and medicinal chemistry.
Formula:C8H8BNO2
InChI:InChI=1/C8H8BNO2/c11-9(12)7-5-10-8-4-2-1-3-6(7)8/h1-5,10-12H
SMILES:c1ccc2c(c1)c(c[nH]2)B(O)O
Synonyms:
  • 1H-Indol-3-ylboronic acid
  • Indole-3-boronic acid
  • 741253-05-4
  • Boronic acid, B-1H-indol-3-yl-
  • (1H-Indol-3-yl)boronicaci
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