CAS 74191-85-8

Doxazosin

Description:

Doxazosin is a selective alpha-1 adrenergic antagonist primarily used in the treatment of hypertension and benign prostatic hyperplasia (BPH). It works by blocking alpha-1 receptors in vascular smooth muscle, leading to vasodilation and a subsequent decrease in blood pressure. Doxazosin is characterized by its chemical formula, which includes a quinazoline structure, and it typically appears as a white to off-white crystalline powder. The substance is soluble in organic solvents like methanol and ethanol but has limited solubility in water. Its pharmacokinetics involve extensive hepatic metabolism, and it has a relatively long half-life, allowing for once-daily dosing. Common side effects may include dizziness, fatigue, and orthostatic hypotension. Doxazosin is often prescribed in conjunction with lifestyle modifications and other antihypertensive agents to enhance therapeutic efficacy. As with any medication, it is essential to monitor for potential interactions and contraindications, particularly in patients with a history of cardiovascular issues.

Formula: C₂₃H₂₅N₅O₅

InChI: InChI=1S/C23H25N5O5/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26)

InChI key: InChIKey=RUZYUOTYCVRMRZ-UHFFFAOYSA-N

SMILES: NC=1C2=C(N=C(N1)N3CCN(C(=O)C4OC=5C(OC4)=CC=CC5)CC3)C=C(OC)C(OC)=C2

Synonyms:

• 1,4-Benzodioxin, piperazine deriv.
• 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine
• 2-[4-(2,3-Dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
• Doxazosin(Subjecttopatentfree)
• DoxazosinMesylate77883-43-3/Base
• Doxazosine
• Doxuran
• Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2,3-dihydro-1,4-benzodioxin-2-yl)-
• Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-
• Uk 33,274
• [4-(4-Amino-6,7-Dimethoxyquinazolin-2-Yl)Piperazin-1-Yl](2,3-Dihydro-1,4-Benzodioxin-2-Yl)Methanone Methanesulfonate (1:1)
• [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2,3-dihydro-1,4-benzodioxin-2-yl)methanone
• [4-(4-Amino-6,7-dimethoxy-quinazolin-2- yl)piperazin-1-yl]-(2,5-dioxabi cyclo[4.4.0]deca-6,8,10-trien-4-yl)methanone

Doxazosin Mesylate

CAS: 74191-85-8, 77883-43-3

Formula: C₂₃H₂₅N₅O₅·CH₄O₃S

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 547.58

Ref: 3B-D4126

Doxazosin

CAS: 74191-85-8

Color and Shape: Neat

Ref: 61-FOR0386.08

2-[4-(2,3-dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine

CAS: 74191-85-8

Formula: C₂₃H₂₅N₅O₅

Purity: %

Color and Shape: Solid

Molecular weight: 451.4751

Ref: IN-DA019DK4

Doxazosin

CAS: 74191-85-8

Doxazosin

Purity: ≥98%

Molecular weight: 451.48g/mol

Ref: 54-BUP10476

Doxazosin

Controlled Product

CAS: 74191-85-8

Formula: C₂₃H₂₅N₅O₅

Color and Shape: Neat

Molecular weight: 451.48

Ref: 86-MM0386.08

Doxazosin

CAS: 74191-85-8

Doxazosin (UK 33274) is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms.

Formula: C₂₃H₂₅N₅O₅

Purity: 99.47% - 99.87%

Color and Shape: Solid

Molecular weight: 451.48

Ref: TM-T22316

Doxazosin

CAS: 74191-85-8

Doxazosin is a research chemical that has shown potential in various fields. It is a water-soluble compound that has been studied for its effects on microcystins, cytidine, and vitamins. Doxazosin has also been found to have aldehyde and particulate properties, making it a versatile compound for different applications. In the field of medicine, Doxazosin has been researched for its potential in treating certain conditions. Studies have shown that Doxazosin can interact with 1-hydroxy-2-naphthoic acid and glutamate, which are important molecules involved in various biological processes. Additionally, Doxazosin has shown promising results in inhibiting the growth of e. cloacae bacteria, making it a potential candidate for antibacterial treatments. Furthermore, Doxazosin has been studied in the field of chemistry due to its unique properties. It can undergo derivatization reactions with fatty acids and z

Formula: C₂₃H₂₅N₅O₅

Purity: Min. 95%

Molecular weight: 451.48 g/mol

Ref: 3D-ZCA19185