CAS 742075-13-4

(5α,6β)-4,5-Epoxy-6-[[(2E)-3-(3-furanyl)-1-oxo-2-propenyl]methylamino]-3,14-dihydroxymorphinan-17-carboxylic Acid 9H-Fluoren-9-ylmethyl Ester

Controlled Product

CAS: 742075-13-4

Applications (5α,6β)-4,5-Epoxy-6-[[(2E)-3-(3-furanyl)-1-oxo-2-propenyl]methylamino]-3,14-dihydroxymorphinan-17-carboxylic Acid 9H-Fluoren-9-ylmethyl Ester is an intermediate in the synthesis of Nalfurafine (N255600), which is a κ-opioid receptor agonist marketed as a treatment for uremic pruritus in hemodialysis patients.
References Kawamura, K., et al.: Chem. Pharma. Bull., 52, 670 (2004);

Formula: C₃₉H₃₆N₂O₇

Color and Shape: Neat

Molecular weight: 644.71

Ref: TR-E589310