CAS 7423-55-4

3-Maleimidopropionic acid

Description:

3-Maleimidopropionic acid is an organic compound characterized by its maleimide functional group, which is known for its reactivity towards thiols, making it valuable in bioconjugation and cross-linking applications. This compound features a propionic acid moiety, contributing to its solubility in polar solvents and its ability to form stable conjugates with biomolecules. It typically appears as a white to off-white solid and has a moderate melting point. The presence of both the maleimide and carboxylic acid groups allows for versatile chemical reactivity, enabling it to participate in various reactions, including Michael additions and amide bond formation. 3-Maleimidopropionic acid is often utilized in the development of bioconjugates, drug delivery systems, and in the modification of proteins and peptides for research and therapeutic purposes. Its ability to selectively react with thiol groups makes it a useful tool in the field of biochemistry and molecular biology. Safety precautions should be observed when handling this compound, as it may pose health risks if ingested or inhaled.

Formula: C₇H₇NO₄

InChI: InChI=1S/C7H7NO4/c9-5-1-2-6(10)8(5)4-3-7(11)12/h1-2H,3-4H2,(H,11,12)

InChI key: InChIKey=IUTPJBLLJJNPAJ-UHFFFAOYSA-N

SMILES: C(CC(O)=O)N1C(=O)C=CC1=O

Synonyms:

• 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-
• 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-propanoic acid
• 2,5-Dioxopyrrole-1-propanoic acid
• 3-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-propionic acid
• 3-(2,5-Dioxo-2H-pyrrol-1(5H)-yl)propanoic acid
• 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid
• 3-(Maleimido)propanoic acid
• 3-Maleimidopropionic acid
• 3-Pyrroline-1-propionic acid, 2,5-dioxo-
• BMPA (imide)
• N-(2-Carboxyethyl)maleimide
• N-Maleoyl-β-alanine

3-Maleimidopropionic Acid

CAS: 7423-55-4

Formula: C₇H₇NO₄

Purity: >97.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 169.14

Ref: 3B-M1962

3-Maleimidopropionic acid, 95%

CAS: 7423-55-4

3-Maleimidopropionic acid is a sulfhydryl reactive heterobifunctional crosslinking reagent. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product

Formula: C₇H₇NO₄

Purity: 95%

Color and Shape: Powder, White to pale yellow

Molecular weight: 169.13

Ref: 02-H61536

3-Maleimido-propionic acid

CAS: 7423-55-4

An amino and sulfhydryl reactive heterobifunctional crosslinking reagent.

Formula: C₇H₇NO₄

Purity: 99.5%

Color and Shape: White Powder

Molecular weight: 169.14

Ref: 01-4038126

3-Maleimidopropionic acid

CAS: 7423-55-4

Formula: C₇H₇NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 169.1348

Ref: IN-DA0033QM

N-Maleoyl-β-alanine

CAS: 7423-55-4

N-Maleoyl-β-alanine

Formula: C₇H₇NO₄

Purity: By hplc: 97% (Typical Value in Batch COA)

Color and Shape: white solid

Molecular weight: 169.13g/mol

Ref: 54-BIM1007

3-Maleimidopropionic acid

CAS: 7423-55-4

3-Maleimidopropionic acid is an alkyl chain-derived PROTAC linker employed in PROTAC synthesis[1].

Formula: C₇H₇NO₄

Color and Shape: White To Pale Yellow Solid

Molecular weight: 169.13

Ref: TM-T14032

3-Maleimidopropionic acid

CAS: 7423-55-4

3-Maleimidopropionic acid, also abbreviated as 3MPA or BMPA, reacts with thiols to form stable conjugates. It is non-cleavable under standard biological conditions.

Formula: C₇H₇NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 169.13 g/mol

Ref: 3D-FM24996

3-Maleimidopropionic acid

CAS: 7423-55-4

Formula: C₇H₇NO₄

Purity: 95%

Color and Shape: Liquid

Molecular weight: 169.136

Ref: 10-F079929

3-Maleimidopropionic Acid

Controlled Product

CAS: 7423-55-4

Applications A sulfhydryl reactive heterobifunctional crosslinking reagent.
References Rich, D., et al.: J. Med. Chem., 18, 1004 (1975), Moroder, L., et al.: BioPolymers, 22, 481 (1983)

Formula: C₇H₇NO₄

Color and Shape: Neat

Molecular weight: 169.13

Ref: TR-M140750