CAS 7424-15-9

L-histidine B-naphthylamide

Description:

L-histidine B-naphthylamide, with the CAS number 7424-15-9, is a derivative of the amino acid histidine, characterized by the presence of a B-naphthylamide group. This compound typically exhibits properties associated with both amino acids and amides, including the ability to participate in hydrogen bonding due to the presence of an amine group. It is often utilized in biochemical research, particularly in studies involving enzyme activity and protein interactions, owing to its structural similarity to histidine, which is a crucial component in many biological processes. The B-naphthylamide moiety can enhance the compound's hydrophobic interactions, potentially influencing its solubility and reactivity in various solvents. Additionally, L-histidine B-naphthylamide may exhibit specific fluorescence properties, making it useful in analytical applications. As with many chemical substances, its stability and reactivity can be influenced by environmental factors such as pH and temperature, which are important considerations in experimental settings.

Formula: C₁₆H₁₆N₄O

InChI: InChI=1/C16H16N4O/c17-15(8-14-9-18-10-19-14)16(21)20-13-6-5-11-3-1-2-4-12(11)7-13/h1-7,9-10,15H,8,17H2,(H,18,19)(H,20,21)/t15-/m0/s1

InChI key: InChIKey=DKDILZBBFKZMRO-HNNXBMFYSA-N

SMILES: N(C([C@H](CC1=CN=CN1)N)=O)C2=CC3=C(C=C2)C=CC=C3

Synonyms:

• (2S)-2-Amino-3-(1H-imidazol-5-yl)-N-naphthalen-2-ylpropanamide
• (αS)-α-Amino-N-2-naphthalenyl-1H-imidazole-5-propanamide
• 1H-Imidazole-4-propanamide, α-amino-N-2-naphthalenyl-, (S)-
• 1H-Imidazole-4-propanamide, α-amino-N-2-naphthalenyl-, (αS)-
• 1H-Imidazole-5-propanamide, α-amino-N-2-naphthalenyl-, (αS)-
• <span class="text-smallcaps">L</span>-Histidine β-naphthylamide
• <span class="text-smallcaps">L</span>-Histidine-2-naphthylamide
• <span class="text-smallcaps">L</span>-Histidyl β-naphthylamide
• H-His-.beta.NA
• H-His-Betana
• Histidine β-naphthylamide
• Imidazole-4-propionamide, α-amino-N-2-naphthyl-, <span class="text-smallcaps">L</span>-
• N-naphthalen-2-yl-L-histidinamide
• N-naphthalen-2-ylhistidinamide
• Imidazole-4-propionamide, α-amino-N-2-naphthyl-, L-
• L-Histidine β-naphthylaMide powder
• L-histidine B-naphthylamide
• H-His-βNA
• L-histidine 2-naphthylamide
• L-His-βNA
• L-HISTIDYL-BETA-NAPHTHYLAMIDE
• (S)-α-Amino-N-(2-naphthalenyl)-1H-imidazole-4-propanamide
• L-Histidine β-naphthylamide
• l-histidine β-naphthylamide
• H-His-bNA
• HISTIDINE-BETANA
• L-HISTIDINE BETA-NAPHTHYLAMIDE

H-His-βNA

CAS: 7424-15-9

In vitro, this compound competitively inhibited sweetalmond β-glucosidase (Ki = 17 µM).

Formula: C₁₆H₁₆N₄O

Purity: > 98%

Color and Shape: White Powder

Molecular weight: 280.33

Ref: 01-4001809

L-Histidine β-naphthylamide

CAS: 7424-15-9

Molecular weight: 280.32

Ref: 7W-GM4190

H-His-ßNA

CAS: 7424-15-9

H-His-ßNA

Purity: ≥95%

Molecular weight: 280.32g/mol

Ref: 54-OR36362

L-Histidine β-naphthylamide

CAS: 7424-15-9

L-Histidine beta-naphthylamide is an allosteric activator of the imidazole group of histidine. It has been shown to regulate sequences and functional groups in subtilisin. L-Histidine beta-naphthylamide binds to the benzyl ester and regulatory allosteric site on the enzyme, which is located between the active site and the substrate binding site. The binding of this molecule stabilizes a transition state intermediate that would otherwise be too reactive to form products.

Formula: C₁₆H₁₆N₄O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 280.32 g/mol

Ref: 3D-FH48736