CAS 74298-63-8

1H-Benzimidazole, 1-[(4-chlorophenyl)methyl]-2-methyl-, hydrochloride (1:1)

Description:

1H-Benzimidazole, 1-[(4-chlorophenyl)methyl]-2-methyl-, hydrochloride (1:1), with CAS number 74298-63-8, is a chemical compound characterized by its benzimidazole core structure, which is a bicyclic compound containing a fused benzene and imidazole ring. This specific derivative features a 4-chlorobenzyl group and a methyl group at the 2-position of the benzimidazole ring, contributing to its unique properties. As a hydrochloride salt, it is typically more soluble in water compared to its free base form, enhancing its bioavailability for pharmaceutical applications. The presence of the 4-chlorophenyl group may influence its biological activity, potentially affecting its interaction with various biological targets. This compound is of interest in medicinal chemistry, particularly for its potential therapeutic applications. Its physical properties, such as melting point, solubility, and stability, can vary based on the specific conditions and formulation. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₁₅H₁₃ClN₂·ClH

InChI: InChI=1S/C15H13ClN2.ClH/c1-11-17-14-4-2-3-5-15(14)18(11)10-12-6-8-13(16)9-7-12;/h2-9H,10H2,1H3;1H

InChI key: InChIKey=MHMTXDMLQZHXRZ-UHFFFAOYSA-N

SMILES: C(N1C=2C(N=C1C)=CC=CC2)C3=CC=C(Cl)C=C3.Cl

Synonyms:

• 1-((4-Chlorophenyl)methyl)-2-methyl-1H-benzimidazole hydrochloride
• 1-(4-Chlorobenzyl)-2-methyl-1H-benzo[d]imidazole hydrochloride
• 1-(4-Chlorobenzyl)-2-methylbenzimidazole hydrochloride
• 1-p-Chlorbenzyl-2-methyl-benzimidazol hydrochlorid
• 1-p-Chlorbenzyl-2-methyl-benzimidazol hydrochlorid [German]
• 1H-Benzimidazole, 1-[(4-chlorophenyl)methyl]-2-methyl-, hydrochloride (1:1)
• 1H-Benzimidazole, 1-[(4-chlorophenyl)methyl]-2-methyl-, monohydrochloride
• 3-(4-chlorobenzyl)-2-methyl-1H-benzimidazol-3-ium chloride
• Benzimidazole, 1-(p-chlorobenzyl)-2-methyl-, hydrochloride
• Chlormidazole HCl
• Clomidazole hydrochloride
• Diamyceline
• Diamyceline hydrochloride
• Fungo-polycid
• Futrican
• Futrican hydrochloride
• H 115
• H115
• Myco-polycid

Chlormidazole hydrochloride

CAS: 74298-63-8

Chlormidazole hydrochloride (Clomidazole hydrochloride) has inhibitory activity against many fungi and some gram-positive cocci.

Formula: C₁₅H₁₄Cl₂N₂

Purity: 99.42%

Color and Shape: Solid

Molecular weight: 293.19

Ref: TM-T10797

Chlormidazole Hydrochloride

Controlled Product

CAS: 74298-63-8

Applications Chlormidazole Hydrochloride has antimicrobial activity against aerobic bacteria and Candida species in vitro. It also has antifungal activity and is used in the treatment of dermatomycosis.
References Krasiejko, I., et al.: Polski Tygodnik Lekarski, 45, 91 (1990); Michalowski, R., et al.: Mater. Ses. Nauk., 76 (1979); Ramisz, A., et al.: Nowosci Weterynarii, 13 (1983)

Formula: C₁₅H₁₄Cl₂N₂

Color and Shape: Neat

Molecular weight: 293.19

Ref: TR-C344000

Chlormidazole hydrochloride

Controlled Product

CAS: 74298-63-8

Chlormidazole hydrochloride is an analytical standard, a drug product, and an API impurity. It is used as a synthetic intermediate in the manufacture of chlormidazole. Chlormidazole hydrochloride is also used as an analytical reference material for HPLC determination of chlormidazole in bulk drug substance or finished drug products. This compound is also used as a synthetic intermediate in the manufacture of chlormidazole and as an analytical reference material for HPLC determination of chlormidazole in bulk drug substances or finished drug products.

Formula: C₁₅H₁₄Cl₂N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 293.2 g/mol

Ref: 3D-ZCA29863