CAS 7433-43-4

N-Hydroxy-N-methylurea

Description:

N-Hydroxy-N-methylurea is an organic compound characterized by its urea derivative structure, featuring a hydroxyl group attached to the nitrogen atom of the methylurea moiety. It is typically a white crystalline solid that is soluble in water and polar organic solvents, reflecting its polar nature due to the presence of the hydroxyl group. This compound is known for its applications in various fields, including pharmaceuticals and agricultural chemistry, often serving as a reagent or intermediate in synthetic processes. N-Hydroxy-N-methylurea exhibits moderate stability under standard conditions but may decompose under extreme pH or temperature conditions. Its reactivity is influenced by the presence of the hydroxyl group, which can participate in hydrogen bonding and other interactions. Safety data indicates that, like many chemical substances, it should be handled with care, as it may pose health risks if ingested or inhaled. Proper safety protocols should be followed when working with this compound in laboratory or industrial settings.

Formula: C₂H₆N₂O₂

InChI: InChI=1S/C2H6N2O2/c1-4(6)2(3)5/h6H,1H3,(H2,3,5)

InChI key: InChIKey=OCWOEDAIWSVHFT-UHFFFAOYSA-N

SMILES: C(N(C)O)(N)=O

Synonyms:

• 1-Methyl-1-hydroxyurea
• 1-Methylhydroxyurea
• Methyl hydroxyurea
• N-Hydroxy-N-methylurea
• NSC 529064
• Sq 17589
• Urea, 1-hydroxy-1-methyl-
• urea, N-hydroxy-N-methyl-
• 1-Hydroxy-1-methylurea

1-Methylhydroxyurea

Controlled Product

CAS: 7433-43-4

Applications 1-Methylhydroxyurea is a methylated hydroxyurea with anticancer activity. 1-Methylhydroxyurea has been shown to inhibit the growth of tumors by impairing DNA replication, without interfering with continued RNA synthesis.
References Hilf, R. et al.: Cancer Res., 26, 2286 (1966); Gale, G.R. et al.: Biochem. Pharmacol., 17, 235 (1968); Yu, R.J. et al.: J. INvest. Dermatol., 63, 279 (1974);

Formula: C₂H₆N₂O₂

Color and Shape: Neat

Molecular weight: 90.08

Ref: TR-M312915