CAS 743420-02-2

N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide

Description:

N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide, with CAS number 743420-02-2, is a synthetic organic compound characterized by its complex structure, which includes multiple functional groups such as amines, amides, and aromatic rings. This compound typically exhibits properties associated with its molecular framework, including potential solubility in organic solvents and moderate stability under standard conditions. Its design suggests potential biological activity, possibly as a pharmaceutical agent, given the presence of the pyridine and fluorophenyl moieties, which are often associated with drug-like properties. The compound may interact with biological targets through hydrogen bonding and π-π stacking due to its aromatic components. Additionally, the presence of the fluorine atom can influence its lipophilicity and metabolic stability. As with many compounds of this nature, its safety profile, including toxicity and environmental impact, would need to be evaluated through appropriate studies.

Formula: C₂₂H₁₉FN₄O₂

InChI: InChI=1S/C22H19FN4O2/c23-18-8-9-19(24)20(12-18)27-22(29)17-6-3-16(4-7-17)14-26-21(28)10-5-15-2-1-11-25-13-15/h1-13H,14,24H2,(H,26,28)(H,27,29)

InChI key: InChIKey=WXHHICFWKXDFOW-UHFFFAOYSA-N

SMILES: N(C(=O)C1=CC=C(CNC(C=CC=2C=CC=NC2)=O)C=C1)C3=C(N)C=CC(F)=C3

Synonyms:

• Benzamide, N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl]-
• N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide
• Benzamide, N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-

Chidamide

CAS: 743420-02-2

Formula: C₂₂H₁₉FN₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 390.4103

Ref: IN-DA00FBIP

HDAC-IN-7

CAS: 743420-02-2

HDAC-IN-7

Purity: ≥95%

Molecular weight: 390.41g/mol

Ref: 54-BUP02635

HDAC-IN-7

CAS: 743420-02-2

HDAC-IN-7 (HBI-8000) (Chidamide impurity) is an impurity of Chidamide.

Formula: C₂₂H₁₉FN₄O₂

Purity: 97.64% - 98.45%

Color and Shape: Solid

Molecular weight: 390.41

Ref: TM-T2025

De-4-fluoro 5-Fluoro Chidamide

CAS: 743420-02-2

Applications De-5-fluoro 4-Fluorochidamide is an analogue of Chidamide (CAS 743420-02-0), a hitsone deacetylase inhibitor (HDACI) that enhances gemcitabine (G305000) cytotoxicity in pancreatic cancer cells.
References Qiao, Z., et. al.: Biochem. Bioph. Res. Co., 434, 95 (2013)

Formula: C₂₂H₁₉FN₄O₂

Color and Shape: Off White Powder

Molecular weight: 390.41

Ref: TR-D289910

CHIDAMIDE

CAS: 743420-02-2

Formula: C₂₂H₁₉FN₄O₂

Purity: 98%

Molecular weight: 390.418

Ref: 10-F500313