CAS 743441-94-3

1-Cyclopropyl-7-[4-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Description:

1-Cyclopropyl-7-[4-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, with CAS number 743441-94-3, is a synthetic compound characterized by its complex molecular structure, which includes a quinoline core, a cyclopropyl group, and a piperazine moiety. This compound exhibits properties typical of quinolone derivatives, including potential antibacterial activity, due to its ability to inhibit bacterial DNA gyrase and topoisomerase IV. The presence of the sulfonyl group enhances its solubility and bioavailability, while the fluorine atom may contribute to its potency and stability. The benzodioxin component suggests potential interactions with biological targets, possibly influencing its pharmacological profile. Overall, this compound is of interest in medicinal chemistry, particularly for its potential therapeutic applications in treating bacterial infections. Further studies would be necessary to fully elucidate its mechanism of action, efficacy, and safety profile in clinical settings.

Formula: C₂₅H₂₄FN₃O₇S

InChI: InChI=1S/C25H24FN3O7S/c26-19-12-17-20(29(15-1-2-15)14-18(24(17)30)25(31)32)13-21(19)27-5-7-28(8-6-27)37(33,34)16-3-4-22-23(11-16)36-10-9-35-22/h3-4,11-15H,1-2,5-10H2,(H,31,32)

InChI key: InChIKey=OQMLZHABXASMDX-UHFFFAOYSA-N

SMILES: O=C1C=2C(N(C=C1C(O)=O)C3CC3)=CC(=C(F)C2)N4CCN(S(=O)(=O)C=5C=C6C(=CC5)OCCO6)CC4

Synonyms:

• 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[4-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-
• 1-Cyclopropyl-7-[4-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid