CAS 74357-20-3

3-Pyridinecarboxylic acid, 6-ethyl-, methyl ester

Description:

3-Pyridinecarboxylic acid, 6-ethyl-, methyl ester, also known as ethyl 6-methylpyridine-3-carboxylate, is an organic compound characterized by its pyridine ring structure, which is a six-membered aromatic ring containing one nitrogen atom. This compound features a carboxylic acid functional group that has been esterified with a methyl group, contributing to its classification as an ester. The presence of the ethyl group at the 6-position of the pyridine ring influences its physical and chemical properties, such as solubility and reactivity. Typically, esters like this compound are known for their pleasant odors and are often used in flavoring and fragrance applications. Additionally, they may exhibit biological activity, making them of interest in medicinal chemistry. The compound is likely to be a colorless to pale yellow liquid or solid, depending on its purity and specific conditions. Safety data should be consulted for handling and storage, as with all chemical substances, to ensure proper precautions are taken.

Formula: C₉H₁₁NO₂

Methyl 6-Ethylnicotinate

Controlled Product

CAS: 74357-20-3

Applications Methyl 6-Ethylnicotinate is used as a building block in the synthesis of several organic compounds including pyrimidine biaryl compounds which act as CDK9 inhibitors. It is also used in the preparation of tetrahydroquinolinyl PGD2 receptor atagonists which can be used in treatment of inflammatory diseases.
References Barsanti, P., et al.: Preparation of pyrimidine biaryl compounds as CDK9 inhibitors, WO Patent 2012101064, Aug 2, 2012; Ghosh, S., et al.: Preparation of tetrahydroquinolinyl PGD2 receptor antagonists for the treatment of inflammatory diseases, US Patent 20050256158, Nov 17, 2005;

Formula: C₉H₁₁NO₂

Color and Shape: Neat

Molecular weight: 165.189

Ref: TR-M268825