CAS 7437-55-0

8-Geranyloxypsoralen

Description:

8-Geranyloxypsoralen is a chemical compound that belongs to the class of psoralens, which are known for their ability to intercalate with DNA and are often used in phototherapy for skin conditions like psoriasis and vitiligo. This compound features a furanocoumarin structure, characterized by a coumarin backbone with a geranyloxy group at the 8-position. It exhibits photosensitizing properties, meaning it can absorb ultraviolet light and subsequently induce biological effects, particularly in the presence of DNA. 8-Geranyloxypsoralen is also noted for its potential role in enhancing the efficacy of certain treatments when combined with UVA light exposure. In terms of physical properties, it is typically a colorless to pale yellow solid, and it is soluble in organic solvents. Safety considerations are important, as psoralens can cause skin sensitivity and increase the risk of skin cancer upon UV exposure. Therefore, handling this compound requires appropriate safety measures to mitigate potential risks associated with its phototoxic effects.

Formula: C₂₁H₂₂O₄

InChI: InChI=1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-19-17(10-12-23-19)13-16-7-8-18(22)25-20(16)21/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+

InChI key: InChIKey=SOVNCTNQAWWYAQ-OQLLNIDSSA-N

SMILES: O(C/C=C(/CCC=C(C)C)\C)C=1C2=C(C=C3C1OC=C3)C=CC(=O)O2

Synonyms:

• 5-Benzofuranacrylic acid, 7-(geranyloxy)-6-hydroxy-, δ-lactone
• 5-Benzofuranacrylicacid, 7-(geranyloxy)-6-hydroxy-, d-lactone
• 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2E)-3,7-dimethyl-2,6-octadienyl]oxy]-
• 7H-Furo[3,2-g][1]benzopyran-7-one,9-[(3,7-dimethyl-2,6-octadienyl)oxy]-, (E)-
• 8-Geranyloxypsoralen
• 9-[[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one
• 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-

XANTHOTOXOL GERANYL ETHER

CAS: 7437-55-0

Formula: C₂₁H₂₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 338.3970

Ref: IN-DA00FCZF

8-Geranopsoralen

CAS: 7437-55-0

Formula: C₂₁H₂₂O₄

Purity: ≥ 95.0%

Color and Shape: Off-white to light brown powder

Molecular weight: 338.40

Ref: 7W-GY5383

8-Geranyloxypsoralen

CAS: 7437-55-0

8-Geranyloxypsoralen

Purity: ≥98%

Molecular weight: 338.4g/mol

Ref: 54-BUP00693

8-Geranopsoralen

CAS: 7437-55-0

Formula: C₂₁H₂₂O₄

Purity: 95%~99%

Molecular weight: 338.403

Ref: BP-BP0107

8-Geranyloxypsoralen

CAS: 7437-55-0

8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat

Formula: C₂₁H₂₂O₄

Purity: 99.87%

Color and Shape: Solid

Molecular weight: 338.4

Ref: TM-TN1343

8-geranyloxypsoralen

CAS: 7437-55-0

Lactone

Formula: C₂₁H₂₂O₄

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 338.4

Ref: 5G-80460

8-Geranyloxypsoralen

CAS: 7437-55-0

8-Geranyloxypsoralen is a natural furanocoumarin, which is a secondary metabolite typically derived from plants, particularly those in the Rutaceae family. Its source lies predominantly in certain fruits and herbs, where it functions as a natural defense compound.

Formula: C₂₁H₂₂O₄

Purity: Min. 95 Area-%

Color and Shape: Off-White Powder

Molecular weight: 338.4 g/mol

Ref: 3D-FG67820