CAS 74405-42-8

Adenosine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-(hydrogen butanedioate)

Description:

Adenosine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-(hydrogen butanedioate) is a complex organic compound characterized by its structural components, which include an adenosine moiety modified with a benzoyl group and a bis(4-methoxyphenyl)phenylmethyl substituent. This compound features a deoxyribose sugar, which is a key characteristic of nucleosides, and is further functionalized with a butanedioate group at the 3' position, indicating potential for specific biochemical interactions. The presence of methoxy groups enhances its lipophilicity, potentially influencing its solubility and permeability across biological membranes. The compound's CAS number, 74405-42-8, allows for its identification in chemical databases, facilitating research and application in fields such as medicinal chemistry and biochemistry. Its unique structure suggests potential utility in drug development, particularly in targeting nucleoside pathways or as a scaffold for further chemical modifications. However, detailed studies on its biological activity, stability, and pharmacokinetics would be necessary to fully understand its properties and potential applications.

Formula: C₄₂H₃₉N₅O₉

InChI: InChI=1/C42H39N5O9/c1-52-31-17-13-29(14-18-31)42(28-11-7-4-8-12-28,30-15-19-32(53-2)20-16-30)54-24-34-33(56-37(50)22-21-36(48)49)23-35(55-34)47-26-45-38-39(43-25-44-40(38)47)46-41(51)27-9-5-3-6-10-27/h3-20,25-26,33-35H,21-24H2,1-2H3,(H,48,49)(H,43,44,46,51)/t33-,34+,35+/m0/s1

InChI key: InChIKey=WYSOXXMLUVYPGV-BMPTZRATSA-N

SMILES: C(OC[C@@H]1[C@@H](OC(CCC(O)=O)=O)C[C@@H](O1)N2C=3C(N=C2)=C(NC(=O)C4=CC=CC=C4)N=CN3)(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7

Synonyms:

• Adenosine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-(hydrogen butanedioate)
• N-Benzoyl-5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-deoxyadenosine 3'-O-succinate
• N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-O-succinate triethylammonium salt
• N6-Benzoyl-5μ-O-(4,4μ-dimethoxytrityl)-2μ-deoxyadenosine 3μ-O-succinic acid
• bz-dmt-deoxyadenosine succinic acid
• N-Benzoyl-3'-O-(3-carboxypropanoyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
• N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxyadenosine 3'-hydrogen butanedioate
• Succinic acid 1-[N-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-3'-adenosyl] ester
• 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE-3'-O-SUCCINIC ACID
• N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-O-succinate

N6-Benzoyl-2''-deoxy-5''-O-DMT-adenosine 3''-O-succinate

CAS: 74405-42-8

Formula: C₄₂H₃₉N₅O₉·C₆H₁₅N

Purity: ≥ 98.0%

Color and Shape: White to off-white or beige powder or crystals

Molecular weight: 858.98

Ref: 7W-GN6419

N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-O-succinate triethylammonium salt

CAS: 74405-42-8

N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-O-succinate triethylammonium salt is a novel nucleoside analog that has antiviral and anticancer properties. It is a ribonucleotide with an N6-(benzoyl)-2'-deoxyadenosine base linked to the 3' position of the sugar through an acetyl group, with a succinic acid moiety at the 5' position. This drug inhibits DNA synthesis and has been shown to block HIV replication in vitro. It also has activity against human papillomavirus type 16 (HPV16) infections in vivo.

Formula: C₄₂H₃₉N₅O₉·C₆H₁₅N

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 858.98 g/mol

Ref: 3D-NB10413