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CAS 74434-59-6

:

sauvagine

Description:
Sauvagine is a peptide that is primarily known for its role as a vasodilator and its influence on blood pressure regulation. It is derived from the skin of certain amphibians, particularly the Phyllomedusa genus, and is structurally related to other peptides such as corticotropin-releasing factor (CRF). Sauvagine exhibits a range of biological activities, including effects on the cardiovascular system, where it can induce vasodilation and influence heart rate. The peptide is characterized by its specific amino acid sequence, which contributes to its biological function and receptor binding properties. It interacts with CRF receptors, playing a role in stress response mechanisms. Additionally, sauvagine has been studied for its potential therapeutic applications, particularly in conditions related to cardiovascular health. Its CAS number, 74434-59-6, is a unique identifier that facilitates the identification and study of this compound in scientific literature and databases. Overall, sauvagine represents an interesting subject of study in the fields of biochemistry and pharmacology due to its physiological effects and potential medical applications.
Formula:C202H346N56O63S1
InChI:InChI=1/C202H346N56O63S/c1-29-103(20)156(162(212)283)251-199(320)161(110(27)261)256-191(312)137(92-155(281)282)247-186(307)132(87-101(16)17)243-185(306)131(86-100(14)15)242-183(304)129(84-98(10)11)239-172(293)116(51-43-78-218-202(215)216)228-188(309)135(90-146(211)266)246-189(310)134(89-145(210)265)238-164(285)109(26)220-163(284)108(25)221-166(287)118(54-63-142(207)262)229-173(294)119(55-64-143(208)263)230-167(288)111(46-34-38-73-203)224-175(296)121(58-67-149(269)270)232-169(290)113(48-36-40-75-205)225-176(297)122(59-68-150(271)272)233-174(295)120(56-65-144(209)264)231-168(289)112(47-35-39-74-204)226-177(298)124(61-70-152(275)276)236-195(316)157(104(21)30-2)252-179(300)125(62-71-153(277)278)237-196(317)158(105(22)31-3)253-180(301)126(72-81-322-28)235-170(291)114(49-37-41-76-206)223-171(292)115(50-42-77-217-201(213)214)227-181(302)127(82-96(6)7)241-184(305)130(85-99(12)13)240-178(299)123(60-69-151(273)274)234-182(303)128(83-97(8)9)245-192(313)138(94-259)249-187(308)133(88-102(18)19)244-190(311)136(91-154(279)280)248-197(318)159(106(23)32-4)254-193(314)139(95-260)250-198(319)160(107(24)33-5)255-194(315)140-52-44-80-258(140)200(321)141-53-45-79-257(141)148(268)93-219-165(286)117-57-66-147(267)222-117/h96-141,156-161,259-261H,29-95,203-206H2,1-28H3,(H2,207,262)(H2,208,263)(H2,209,264)(H2,210,265)(H2,211,266)(H2,212,283)(H,219,286)(H,220,284)(H,221,287)(H,222,267)(H,223,292)(H,224,296)(H,225,297)(H,226,298)(H,227,302)(H,228,309)(H,229,294)(H,230,288)(H,231,289)(H,232,290)(H,233,295)(H,234,303)(H,235,291)(H,236,316)(H,237,317)(H,238,285)(H,239,293)(H,240,299)(H,241,305)(H,242,304)(H,243,306)(H,244,311)(H,245,313)(H,246,310)(H,247,307)(H,248,318)(H,249,308)(H,250,319)(H,251,320)(H,252,300)(H,253,301)(H,254,314)(H,255,315)(H,256,312)(H,269,270)(H,271,272)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H4,213,214,217)(H4,215,216,218)/t103-,104-,105-,106-,107-,108-,109-,110+,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,156-,157-,158-,159-,160-,161-/m0/s1
Synonyms:
  • Pyr-Gly-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Ser-Leu-Glu-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2
  • PGLU-GLY-PRO-PRO-ILE-SER-ILE-ASP-LEU-SER-LEU-GLU-LEU-LEU-ARG-LYS-MET-ILE-GLU-ILE-GLU-LYS-GLN-GLU-LYS-GLU-LYS-GLN-GLN-ALA-ALA-ASN-ASN-ARG-LEU-LEU-LEU-ASP-THR-ILE-NH2
  • GLP-GLY-PRO-PRO-ILE-SER-ILE-ASP-LEU-SER-LEU-GLU-LEU-LEU-ARG-LYS-MET-ILE-GLU-ILE-GLU-LYS-GLN-GLU-LYS-GLU-LYS-GLN-GLN-ALA-ALA-ASN-ASN-ARG-LEU-LEU-LEU-ASP-THR-ILE-NH2
  • H-PYR-GLY-PRO-PRO-ILE-SER-ILE-ASP-LEU-SER-LEU-GLU-LEU-LEU-ARG-LYS-MET-ILE-GLU-ILE-GLU-LYS-GLN-GLU-LYS-GLU-LYS-GLN-GLN-ALA-ALA-ASN-ARG-LEU-LEU-LEU-ASP-THR-ILE-NH2
  • Sauvagine >=97% (HPLC)
  • Sauvagine trifluoroacetate salt
  • M.W. 4599.31 C202H346N56O63S
  • SAUVAGINE (FROG)
  • SAUVAGINE
  • PYR-GPPISIDLSLELLRKMIEIEKQEKEKQQAANNRLLLDTI-NH2
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Found 4 products.
  • Sauvagine
    Bachem
    + Info

    Sauvagine

    CAS:
    An active polypeptide isolated from the skin of the neotropical frog Phyllomedusa sauvagei. It exhibits a number of pharmacological actions on diuresis, the cardiovascular system and the endocrine glands.
    Formula:C202H346N56O63S
    Purity:> 96%
    Color and Shape:White Powder
    Molecular weight:4599.38

    Ref: 01-4027592

    1mg
    432.00€
    0.5mg
    242.00€
  • CymitQuimica logo
    Glentham
    + Info

    Sauvagine

    CAS:
    Formula:C202H346N56O63S
    Molecular weight:4599.31

    Ref: 7W-GL4688

    ne
    To inquire
  • Sauvagine
    Targetmol
    + Info

    Sauvagine

    CAS:
    CRF receptor agonist; Ki: 9.4 nM (hCRF-R1), 9.9 nM (rCRF-R2a), 3.8 nM (mCRF-R2b) for 125I-[D-Tyr1]astressin binding inhibition.
    Formula:C202H346N56O63S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4599.35

    Ref: TM-TP2121

  • Sauvagine trifluoroacetate salt
    Biosynth
    + Info

    Sauvagine trifluoroacetate salt

    CAS:
    Sauvagine is a trifluoroacetate salt of Pyr-Gly-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Ser-Leu-Glu-Leu-Leu-Arg. It has been used as a model system to study the effects of trifluoroacetic acid on brain functions. Sauvagine has also been shown to have inhibitory effects on cyclase enzymes, which are involved in the synthesis of steroids and other hormones. This compound has also been found to have an effect on locomotor activity and receptor activity.
    Formula:C202H346N56O63S
    Purity:Min. 95%
    Molecular weight:4,599.31 g/mol

    Ref: 3D-FS109392

    1mg
    860.00€
    2mg
    1,024.00€
    5mg
    2,182.00€