CAS 74436-00-3

33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone

Description:

The chemical substance with the name "33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone" and CAS number "74436-00-3" is a complex organic compound characterized by a large and intricate molecular structure. It features multiple functional groups, including hydroxyl and alkene moieties, which contribute to its reactivity and potential biological activity. The presence of numerous methyl and propyl groups suggests a hydrophobic character, which may influence its solubility and interaction with biological membranes. The compound's extensive azacyclotritriacontane framework indicates a significant degree of nitrogen incorporation, potentially affecting its stability and interaction with other molecules. Such compounds are often studied for their potential applications in pharmaceuticals, materials science, or as surfactants, owing to their unique structural properties. However, detailed studies would be necessary to fully understand its properties, behavior, and potential applications in various fields.

Formula: C₆₃H₁₁₃N₁₁O₁₂

InChI: InChI=1/C63H113N11O12/c1-25-27-29-41(15)53(76)52-57(80)66-44(28-26-2)59(82)68(18)34-49(75)69(19)45(30-35(3)4)56(79)67-50(39(11)12)62(85)70(20)46(31-36(5)6)55(78)64-42(16)54(77)65-43(17)58(81)71(21)47(32-37(7)8)60(83)72(22)48(33-38(9)10)61(84)73(23)51(40(13)14)63(86)74(52)24/h25,27,35-48,50-53,76H,26,28-34H2,1-24H3,(H,64,78)(H,65,77)(H,66,80)(H,67,79)/b27-25+

Synonyms:

• 74436-00-3
• 7-L-Norvaline Cyclosporin A
• Nva2-Cyclosporine

Cyclosporin G

CAS: 74436-00-3

Formula: C₆₃H₁₁₃N₁₁O₁₂

Color and Shape: White To Off-White Solid

Molecular weight: 1216.66

Ref: 4Z-PC-546

Cyclosporin G

Controlled Product

CAS: 74436-00-3

Formula: C₆₃H₁₁₃N₁₁O₁₂

Color and Shape: Neat

Molecular weight: 1216.64

Ref: TR-C990143

Cyclosporin G

CAS: 74436-00-3

Formula: C₆₂H₁₁₁N₁₁O₁₂

Molecular weight: 1202.6

Ref: ST-EA-CP-C162009

Cyclosporin G

CAS: 74436-00-3

Cyclosporin G is an immunosuppressive agent, which is derived from fungal sources with a specific mode of action that involves inhibiting calcineurin. The source of Cyclosporin G is primarily from the fermentation of the fungus *Tolypocladium inflatum*. Its mode of action involves binding to the cytosolic protein cyclophilin in T-lymphocytes, which subsequently inhibits the phosphatase activity of calcineurin. This inhibition prevents the dephosphorylation and nuclear translocation of the nuclear factor of activated T-cells (NFAT), thereby reducing the transcription of interleukin-2 and other cytokines critical for T-cell activation.

Formula: C₆₃H₁₁₃N₁₁O₁₂

Purity: Min. 95%

Molecular weight: 1,216.64 g/mol

Ref: 3D-BC171087