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CAS 7448-02-4

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4,4-Dimethylzymosterol

Description:
4,4-Dimethylzymosterol is a sterol compound that plays a significant role in the biosynthesis of sterols and is often studied in the context of cholesterol metabolism. It is characterized by its unique structure, which includes a steroid nucleus with two methyl groups at the 4-position, contributing to its distinct physical and chemical properties. This compound is typically found in various biological systems, particularly in fungi and plants, where it serves as a precursor in the synthesis of more complex sterols. 4,4-Dimethylzymosterol is insoluble in water but soluble in organic solvents, reflecting its lipophilic nature. Its presence is important in the study of lipid metabolism and the development of pharmaceuticals targeting cholesterol-related disorders. Additionally, it may exhibit biological activities that warrant further investigation, particularly in relation to its effects on cell membranes and signaling pathways. Overall, 4,4-Dimethylzymosterol is a valuable compound in both biochemical research and potential therapeutic applications.
Formula:C29H48O
InChI:InChI=1/C29H48O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,20,22-23,25-26,30H,8,10-18H2,1-7H3/t20-,22-,23+,25+,26+,28-,29-/m1/s1
InChI key:InChIKey=CHGIKSSZNBCNDW-QGBOJXOESA-N
SMILES:C[C@@]12C3=C([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC=C(C)C)C)(CC4)[H])[H])CC[C@]1(C(C)(C)[C@@H](O)CC2)[H]
Synonyms:
  • (3β,5α)-4,4-Dimethylcholesta-8,24-dien-3-ol
  • 14-Desmethyllanosterol
  • 14-Norlanosterol
  • 14α-Demethyllanosterol
  • 4,4-Dimethyl-5Alpha -Cholesta-8,24-Dien-3-Beta -Ol
  • 4,4-Dimethyl-5a-cholesta-8,24-dien-3-b-ol
  • 4,4-Dimethyl-5α-cholesta-8(9),24-dien-3β-ol
  • 4,4-Dimethyl-5α-cholesta-8,24-dien-3β-ol
  • 4,4-Dimethylcholesta-8,24-dienol
  • 4,4-Dimethylzymosterol
  • See more synonyms
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Found 2 products.
  • 14-Norlanosterol
    TRC
    + Info

    14-Norlanosterol

    Controlled Product
    CAS:

    Applications 14-Norlanosterol, is a metabolite of Lanosterol (L174580). It is also a meiosis activating sterol (MAS), which is shown to have an important role in regulating meiosis and reproduction.
    References Byskov, A., et al.: Mol. Cell. Endocrinology, 187, 189 (2002);

    Formula:C29H48O
    Color and Shape:Neat
    Molecular weight:412.691

    Ref: TR-N661435

    25mg
    26,646.00€
  • 14-Norlanosterol
    Biosynth
    + Info

    14-Norlanosterol

    Controlled Product
    CAS:
    14-Norlanosterol is a cholesterol biosynthesis inhibitor that has shown to be effective in reducing serum cholesterol levels. The enzyme that this drug inhibits is the cholesterol acyltransferase (CAT). The CAT enzyme transfers an acyl group from acetyl coenzyme A to the 3-hydroxy group of cholesterol, producing 14-norlanosterol. This process is important for the production of bile acids and for the synthesis of steroid hormones, such as testosterone. 14-Norlanosterol has been shown to inhibit the activity of CAT by binding to its active site, preventing formation of a ternary complex with acetyl coenzyme A and cholesterol. This inhibition prevents the transfer of an acyl group from acetyl coenzyme A to cholesterol, which leads to lower serum cholesterol levels. 14-Norlanosterol also inhibits other enzymes involved in sterol synthesis, including methyltransferase, epoxidase activity, and demethylation.
    Formula:C29H48O
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:412.7 g/mol

    Ref: 3D-HAA44802

    1mg
    2,124.00€