CAS 7449-74-3

N-Methyl-N-(trimethylsilyl)acetamide

Description:

N-Methyl-N-(trimethylsilyl)acetamide, with the CAS number 7449-74-3, is an organic compound that belongs to the class of amides. It features a methyl group and a trimethylsilyl group attached to the nitrogen atom, which enhances its solubility and reactivity. This compound is typically a colorless to pale yellow liquid and is known for its ability to act as a derivatizing agent in analytical chemistry, particularly in gas chromatography. Its structure allows for the stabilization of reactive intermediates, making it useful in various synthetic applications. N-Methyl-N-(trimethylsilyl)acetamide is also characterized by its relatively low volatility and moderate polarity, which contribute to its effectiveness in forming stable derivatives with polar functional groups. Additionally, it is often employed in the preparation of silyl derivatives of alcohols, amines, and carboxylic acids, facilitating their analysis and characterization. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested.

Formula: C₆H₁₅NOSi

InChI: InChI=1S/C6H15NOSi/c1-6(8)7(2)9(3,4)5/h1-5H3

InChI key: InChIKey=QHUOBLDKFGCVCG-UHFFFAOYSA-N

SMILES: N([Si](C)(C)C)(C(C)=O)C

Synonyms:

• Acetamide, N-methyl-N- (trimethylsilyl)-
• N-Trimethylsilyl-N-methylacetamide
• NSC 142435
• N-Methyl-N-(trimethylsilyl)acetamide
• N-Methyl-N-(trimethylsilyl)acetamide

N-Methyl-N-trimethylsilylacetamide [Trimethylsilylating Agent]

CAS: 7449-74-3

Formula: C₆H₁₅NOSi

Purity: >90.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 145.28

Ref: 3B-M0536

N-Methyl-N-trimethylsilylacetamide, 98%

CAS: 7449-74-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₁₅NOSi

Purity: 98%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 145.28

Ref: 02-L04101

N-Methyl-N-trimethylsilylacetamide (>85%)

CAS: 7449-74-3

Formula: C₆H₁₅NOSi

Purity: 90%

Color and Shape: Solid

Molecular weight: 145.2749

Ref: IN-DA003T83

N-Methyl-N-trimethylsilylacetamide

CAS: 7449-74-3

N-Methyl-N-trimethylsilylacetamide

Purity: 97%

Molecular weight: 145.28g/mol

Ref: 54-OR72534

N-Methyl-N-(Trimethylsilyl)Acetamide

CAS: 7449-74-3

N-Methyl-N-(Trimethylsilyl)Acetamide

Purity: 97%

Molecular weight: 145.27g/mol

Ref: 54-OR1030545

N-Methyl-N-trimethylsilyacetamide

CAS: 7449-74-3

S11925 - N-Methyl-N-trimethylsilyacetamide

Formula: C₆H₁₅NOSi

Purity: 97%

Color and Shape: White powder

Molecular weight: 145.277

Ref: 10-S11925

N-Methyl-N-trimethylsilylacetamide

Controlled Product

CAS: 7449-74-3

Applications N-Methyl-N-trimethylsilylacetamide, is a powerful silylating agent for polar compounds.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Melanie MacGregor-Ramiasa et. al; Acta biomaterialia, 56, undefined (2017-2-25)

Formula: C₆H₁₅NOSi

Purity: >85%

Color and Shape: Neat

Molecular weight: 145.27

Ref: TR-M321985

N-Methyl-N-trimethylsilylacetamide

CAS: 7449-74-3

N-Methyl-N-trimethylsilylacetamide is a bifunctional amide that can react with an electrophile, such as hexane, to form an N-methylated product. The amide group of the molecule can also be deprotonated by a strong base to form an enolate, which can then react with a nucleophile. The NMR spectra of this compound show that it has a multinuclear structure and contains two tautomers. It is used in analytical chemistry for sample preparation, chromatographic science for reaction intermediates, and chemical study for its reactivity.

Formula: C₆H₁₅NOSi

Purity: Min. 97 Area-%

Color and Shape: Clear Liquid

Molecular weight: 145.27 g/mol

Ref: 3D-FM61105