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CAS 745-65-3

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Prostaglandin E1

Description:
Prostaglandin E1 (PGE1), with the CAS number 745-65-3, is a naturally occurring lipid compound that plays a crucial role in various physiological processes. It is classified as a prostaglandin, which are bioactive lipids derived from arachidonic acid. PGE1 is known for its potent vasodilatory effects, making it significant in regulating blood flow and blood pressure. It is also involved in inflammatory responses, modulating immune function, and influencing gastrointestinal motility. The compound is typically a colorless to pale yellow oil and is soluble in organic solvents but has limited solubility in water. PGE1 has therapeutic applications, particularly in the treatment of erectile dysfunction and as a vasodilator in certain cardiovascular conditions. Its mechanism of action involves the activation of specific receptors, leading to increased intracellular cyclic AMP levels. Due to its biological activity, PGE1 is also studied for its potential roles in reproductive health and as a protective agent in various organ systems.
Formula:C20H34O5
InChI:InChI=1/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/p-1/b13-12+/t15-,16+,17+,19+/m0/s1
InChI key:InChIKey=GMVPRGQOIOIIMI-DWKJAMRDSA-N
SMILES:C(CCCCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)CC1=O
Synonyms:
  • (-)-Prostaglandin E<sub>1</sub>
  • (11alpha,12xi,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid
  • (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oate
  • (11alpha,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid
  • (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid
  • 11,15-Dihydroxy-9-Oxoprost-13-En-1-Oic Acid
  • 11α,15(S)-Dihydroxy-9-oxo-13-trans-prostenoic acid
  • 11α,15α-Dihydroxy-9-oxo-13-trans-prostenoic acid
  • Aiprostadil
  • Alprostadil
  • See more synonyms
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