CAS 745017-94-1

MMAF

Description:

MMAF, or Monomethyl Auristatin F, is a synthetic compound primarily used in the field of cancer research and drug development, particularly in antibody-drug conjugates (ADCs). It is a potent cytotoxic agent derived from the natural product dolastatin 10, which is known for its ability to inhibit cell division by disrupting microtubule dynamics. MMAF exhibits a high degree of specificity and efficacy against cancer cells, making it a valuable tool in targeted cancer therapies. The compound is characterized by its ability to induce apoptosis in malignant cells while sparing normal tissues, which is a significant advantage in reducing side effects associated with traditional chemotherapy. Additionally, MMAF is soluble in organic solvents, which facilitates its incorporation into various drug formulations. Its mechanism of action involves binding to tubulin, leading to cell cycle arrest and subsequent cell death. Overall, MMAF represents a promising candidate in the ongoing efforts to improve cancer treatment outcomes through targeted delivery systems.

Monomethylauristatin F

CAS: 745017-94-1

Formula: C₃₉H₆₅N₅O₈

Purity: 95%

Color and Shape: Solid

Molecular weight: 731.9621

Ref: IN-DA00359W

MMAF

CAS: 745017-94-1

MMAF

Purity: ≥95%

Molecular weight: 731.96g/mol

Ref: 54-BUP06543

Monomethyl Auristatin F

CAS: 745017-94-1

Formula: C₃₉H₆₅N₅O₈

Molecular weight: 731.98

Ref: 4Z-PA-329003

MMAF

CAS: 745017-94-1

MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.

Formula: C₃₉H₆₅N₅O₈

Purity: 97.00% - 99.88%

Color and Shape: Solid

Molecular weight: 731.96

Ref: TM-T3256

Monomethyl Auristatin F

CAS: 745017-94-1

Synthetic antineoplastic agent

Formula: C₃₉H₆₅N₅O₈

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 731.96 g/mol

Ref: 3D-FM76372

Monomethylauristatin F

CAS: 745017-94-1

Purity: 99%

Molecular weight: 731.48

Ref: 10-F567434

Monomethyl Auristatin F

Controlled Product

CAS: 745017-94-1

Formula: C₃₉H₆₅N₅O₈

Color and Shape: Neat

Molecular weight: 731.96

Ref: TR-M564805