CAS 745038-86-2

Isopropylmagnesium chloride-lithium chloride complex, with the CAS number 745038-86-2, is a Grignard reagent that combines isopropylmagnesium chloride with lithium chloride. This complex is typically used in organic synthesis, particularly in reactions involving nucleophilic additions to carbonyl compounds. The presence of lithium chloride enhances the reactivity and stability of the Grignard reagent, facilitating the formation of organomagnesium compounds. The complex is characterized by its air and moisture sensitivity, requiring an anhydrous environment for storage and handling. It is usually prepared and used in an inert atmosphere, such as nitrogen or argon, to prevent decomposition. The reactivity of this complex allows it to participate in various coupling reactions, making it valuable in the synthesis of complex organic molecules. Additionally, the isopropyl group contributes to steric hindrance, influencing the selectivity and outcome of reactions. Proper safety precautions should be taken when working with this reagent due to its highly reactive nature.