CAS 74513-62-5

Trimegestone

Description:

Trimegestone is a synthetic progestin, primarily used in hormone replacement therapy and contraceptive formulations. It is characterized by its ability to mimic the effects of natural progesterone, thereby playing a crucial role in regulating various physiological processes, including the menstrual cycle and pregnancy. Trimegestone exhibits high oral bioavailability and a favorable pharmacokinetic profile, which allows for effective dosing in therapeutic applications. The compound is known for its anti-estrogenic properties, making it useful in managing conditions influenced by estrogen levels. Additionally, it has a relatively low androgenic activity, which minimizes side effects commonly associated with other progestins. Trimegestone is typically administered in combination with estrogen in hormone replacement therapies to alleviate menopausal symptoms and to provide endometrial protection. Its chemical structure includes a steroid backbone, which is common among progestins, contributing to its biological activity. As with any hormonal medication, careful consideration of dosage and potential side effects is essential for safe and effective use.

Formula: C₂₂H₃₀O₃

InChI: InChI=1S/C22H30O3/c1-13(23)20(25)22(3)11-9-19-18-6-4-14-12-15(24)5-7-16(14)17(18)8-10-21(19,22)2/h12-13,18-19,23H,4-11H2,1-3H3/t13-,18+,19-,21-,22+/m0/s1

InChI key: InChIKey=JUNDJWOLDSCTFK-MTZCLOFQSA-N

SMILES: C[C@@]12[C@]([C@]3(C(CC1)=C4C(CC3)=CC(=O)CC4)[H])(CC[C@@]2(C([C@H](C)O)=O)C)[H]

Synonyms:

• (17beta)-17-[(2S)-2-hydroxypropanoyl]-17-methylestra-4,9-dien-3-one
• (17β)-17-[(2S)-2-Hydroxy-1-oxopropyl]-17-methylestra-4,9-dien-3-one
• 17beta-(S)-Lactoyl-17-methylestra-4,9-dien-3-one
• Estra-4,9-dien-3-one, 17-(2-hydroxy-1-oxopropyl)-17-methyl-, (17beta(S))-
• Estra-4,9-dien-3-one, 17-(2-hydroxy-1-oxopropyl)-17-methyl-, [17β(S)]-
• Estra-4,9-dien-3-one, 17-[(2S)-2-hydroxy-1-oxopropyl]-17-methyl-, (17β)-
• Ru 27987
• Totelle Sekvens, Ondeva
• Trimegestone [INN]
• Unii-4658K0H08W
• Trimegestone

Trimegestone-d3

CAS: 74513-62-5

Formula: C₂₂H₂₇D₃O₃

Molecular weight: 345.50

Ref: 4Z-T-168005

Trimegestone

CAS: 74513-62-5

Formula: C₂₂H₃₀O₃

Color and Shape: White To Off-White Solid

Molecular weight: 342.48

Ref: 4Z-T-168001

Trimegestone-13C-d3

CAS: 74513-62-5

Formula: C₂₁₁₃CH₂₇D₃O₃

Molecular weight: 346.49

Ref: 4Z-T-168004

Trimegestone

Controlled Product

CAS: 74513-62-5

Formula: C₂₂H₃₀O₃

Color and Shape: Neat

Molecular weight: 342.472

Ref: TR-T795715

Trimegestone

Controlled Product

CAS: 74513-62-5

Trimegestone is a progestin that has been shown to have clinical properties such as a decrease in the symptoms of endometriosis. It decreases angiotensin II and follicle-stimulating hormone (FSH) levels, which leads to an increase in follicular growth and ovulation. Trimegestone also has contraceptive properties and can be used for women who are trying to conceive. The drug was developed from natural compounds found in plants and animals. Trimegestone is not currently available for commercial use due to its lack of specificity and possible side effects.

Formula: C₂₂H₃₀O₃

Purity: Min. 95%

Molecular weight: 342.47 g/mol

Ref: 3D-FT39363

Trimegestone

CAS: 74513-62-5

Trimegestone, a highly effective oral progestogen, is used for endometrial protection, all doses inducing secretory endometrial transformation.

Formula: C₂₂H₃₀O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 342.47

Ref: TM-T20755