CAS 74534-15-9

1-Chloro-2-iodo-4-nitrobenzene

Description:

1-Chloro-2-iodo-4-nitrobenzene is an organic compound characterized by the presence of a benzene ring substituted with three distinct functional groups: a chlorine atom, an iodine atom, and a nitro group. The chlorine and iodine atoms are halogens, which can influence the compound's reactivity and polarity. The nitro group is a strong electron-withdrawing group, which can enhance the compound's electrophilic character. This compound is typically a solid at room temperature and may exhibit a yellowish color. It is soluble in organic solvents but has limited solubility in water due to its hydrophobic aromatic structure. The presence of multiple halogens and a nitro group suggests that 1-chloro-2-iodo-4-nitrobenzene may participate in various chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions. Additionally, its unique combination of substituents may impart specific biological activities, making it of interest in medicinal chemistry and material science. Safety precautions should be taken when handling this compound, as it may pose health risks due to its halogenated nature.

Formula: C₆H₃ClINO₂

InChI: InChI=1/C6H3ClINO2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H

SMILES: c1cc(c(cc1N(=O)=O)I)Cl

Synonyms:

• Benzene, 1-Chloro-2-Iodo-4-Nitro-
• 4-Chloro-3-Iodonitrobenzene
• 1-Chloro-2-Iodo-4-Nitro-Benzene
• 3-Iodo-4-chloronitrobenzene
• Nsc223078

1-chloro-2-iodo-4-nitrobenzene

CAS: 74534-15-9

Formula: C₆H₃ClINO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 283.4510

Ref: IN-DA008PSF

4-Chloro-3-iodonitrobenzene

CAS: 74534-15-9

4-Chloro-3-iodonitrobenzene

Formula: C₆H₃ClINO₂

Purity: ≥95%

Color and Shape: orangey tan powder

Molecular weight: 283.45g/mol

Ref: 54-OR18059

4-Chloro-3-iodonitrobenzene

CAS: 74534-15-9

Formula: C₆H₃ClINO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 283.45

Ref: 10-F050130

1-Chloro-2-iodo-4-nitrobenzene

Controlled Product

CAS: 74534-15-9

Applications 1-Chloro-2-iodo-4-nitrobenzene is an intermediate for Vismodegib (V674700) and Vismodegib-d4 (V674702), pharmaceuticals that target the hedgehog (Hh) pathway.
References Gupta, S. et al.: Ther. Advances in Med. Oncology, 2, 237 (2010);

Formula: C₆H₃ClINO₂

Color and Shape: Neat

Molecular weight: 283.45

Ref: TR-C380603

4-Chloro-3-iodonitrobenzene

CAS: 74534-15-9

Versatile small molecule scaffold

Formula: C₆H₃ClINO₂

Purity: Min. 95%

Molecular weight: 283.45 g/mol

Ref: 3D-ZCA53415