CAS 74578-69-1

Ceftriaxone sodium

Description:

Ceftriaxone sodium is a broad-spectrum cephalosporin antibiotic used primarily for the treatment of various bacterial infections. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a wide range of Gram-positive and Gram-negative bacteria. The compound is typically administered via intravenous or intramuscular routes due to its poor oral bioavailability. Ceftriaxone sodium is known for its long half-life, allowing for once-daily dosing in many cases. It is soluble in water, which facilitates its use in injectable formulations. The substance is generally well-tolerated, though it may cause side effects such as allergic reactions, gastrointestinal disturbances, and alterations in blood coagulation. Ceftriaxone sodium is also notable for its ability to penetrate well into various body tissues and fluids, including the central nervous system, making it effective for treating infections like meningitis. However, it is important to monitor for potential interactions with other medications and to consider resistance patterns in the bacteria being treated.

Formula: C₁₈H₁₈N₈O₇S₃·2Na

InChI: InChI=1S/C18H18N8O7S3.2Na/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7;;/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32);;/b24-8-;;/t9-,15-;;/m1../s1

InChI key: InChIKey=VUGBLGCUPUUDOI-BBJOQENWSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1CSC=4N(C)NC(=O)C(=O)N4)[H].[Na]

Synonyms:

• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, disodium salt, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, disodium salt, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, sodium salt (1:2), (6R,7R)-
• Acantex
• Aventriax
• Cefatriaxone
• Cefexone
• Cefotrix
• Ceftiaxone Sodium
• Ceftriaxone disodium
• Ceftriaxone disodium salt
• CeftriaxoneSodium
• Cephtriaxone
• Ceroneed
• Disodium ceftriaxone
• Lendacin
• Longaceph
• Mesporin
• Monocef
• Oframax
• Ro 13-9904
• Rocephin
• Rochephin
• Sefirom
• Tartriakson
• X 13-9904
• disodium (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-6-oxido-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Ceftriaxone Disodium Salt Hemiheptahydrate

CAS: 104376-79-6, 73384-59-5, 74578-69-1

Formula: C₁₈H₁₆N₈Na₂O₇S₃H₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 661.58

Ref: 3B-C2226

Ceftriaxone (sodium salt)

CAS: 74578-69-1

Formula: C₁₈H₁₈N₈Na₂O₇S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 600.5595

Ref: IN-DA00ICJB

Ceftriaxone Sodium Salt

CAS: 74578-69-1

Ceftriaxone Sodium Salt

Purity: 95%

Molecular weight: 576.57g/mol

Ref: 54-OR1004231

Ceftriaxone Sodium Salt

CAS: 74578-69-1

Formula: C₁₈H₁₇N₈NaO₇S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 576.55

Ref: 10-F066522

Ceftriaxone Disodium

CAS: 74578-69-1

Formula: C₁₈H₁₆N₈O₇S₃₂(Na)

Molecular weight: 552.56 : 2(22.99)

Ref: ST-EA-CP-C217006

Ceftriaxone sodium

CAS: 74578-69-1

Ceftriaxone sodium is a third-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating severe bacterial infections like meningitis and pneumonia.

Formula: C₁₈H₁₈N₈Na₂O₇S₃

Purity: Min. 84 Area-%

Color and Shape: White Yellow Powder

Molecular weight: 600.56 g/mol

Ref: 3D-AC64975