CAS 74681-68-8

Benzenesulfonamide, 4-[5-(4-methyl-1-piperazinyl)[2,5′-bi-1H-benzimidazol]-2′-yl]-, hydrochloride (1:3)

Description:

Benzenesulfonamide, 4-[5-(4-methyl-1-piperazinyl)[2,5′-bi-1H-benzimidazol]-2′-yl]-, hydrochloride (1:3), with CAS number 74681-68-8, is a chemical compound characterized by its complex structure, which includes a benzenesulfonamide moiety and a bi-benzimidazole framework. This compound typically exhibits properties associated with sulfonamides, such as antibacterial activity, and may also demonstrate potential in various therapeutic applications due to its piperazine substituent, which can enhance bioactivity and solubility. The hydrochloride salt form indicates that it is a hydrochloride, which often improves the stability and solubility of the compound in aqueous solutions. The presence of the piperazine ring suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Additionally, the compound's molecular structure may influence its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME). Overall, this compound represents a class of sulfonamide derivatives that may have significant implications in pharmaceutical research and development.

Formula: C₂₅H₂₅N₇O₂S·3ClH

InChI: InChI=1/C25H25N7O2S.3ClH/c1-31-10-12-32(13-11-31)18-5-9-21-23(15-18)30-25(28-21)17-4-8-20-22(14-17)29-24(27-20)16-2-6-19(7-3-16)35(26,33)34;;;/h2-9,14-15H,10-13H2,1H3,(H,27,29)(H,28,30)(H2,26,33,34);3*1H

InChI key: InChIKey=NZVGXJAQIQJIOY-UHFFFAOYSA-N

SMILES: CN1CCN(C=2C=C3NC(=NC3=CC2)C=4C=C5C(=CC4)N=C(N5)C6=CC=C(S(N)(=O)=O)C=C6)CC1.Cl

Synonyms:

• 4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)benzenesulfonamide trihydrochloride
• 4-[5-(4-Methyl-1-piperazinyl)[2,5′-bi-1H-benzimidazol]-2′-yl]-benzenesulfonamide
• 4-[6-(4-methylpiperazin-1-yl)-1H,3'H-2,5'-bibenzimidazol-2'-yl]benzenesulfonamide trihydrochloride
• Benzenesulfonamide, 4-[5-(4-methyl-1-piperazinyl)[2,5′-bi-1H-benzimidazol]-2′-yl]-, hydrochloride (1:3)
• Benzenesulfonamide, 4-[5-(4-methyl-1-piperazinyl)[2,5′-bi-1H-benzimidazol]-2′-yl]-, trihydrochloride
• Hoe-S769121
• Hoechst S 769121
• Nuclear yellow
• s769121
• 4-[5-(4-methyl-1-piperazinyl)[2,50-bi-1hbenzimidazol]-
• Hoechst
• NUCLEAR YELLOW APPROX. 80%
• Benzenesulfonamide, 4-[5-(4-methyl-1-
• Nuclear Yellow [Hoechst S769121] *CAS 74681-68-8*
• 20-yl]-benzenesulfonamide
• piperazinyl)[2,50-bi-1h-benzimidazol]-20-yl]-, Trihydrochloride
• approx.80%
• Nuclear yellow, BR

Nuclear yellow

CAS: 74681-68-8

Formula: C₂₅H₂₈Cl₃N₇O₂S

Purity: 95.0%

Molecular weight: 596.9595

Ref: IN-DA00FC0N

Hoechst S 769121

CAS: 74681-68-8

Hoechst S 769121 (Nuclear yellow) is a fluorescence dye that can bound to DNA (excitation/emission maxima ~335/495 nm).

Formula: C₂₅H₂₈Cl₃N₇O₂S

Color and Shape: Solid

Molecular weight: 596.96

Ref: TM-T19041

Nuclear yellow

CAS: 74681-68-8

Hoechst S 769121 is a research chemical that has various applications in the field of pharmaceutical research. It has been studied for its potential in combination with other drugs such as canagliflozin, lenvatinib, dimethyl fumarate, glimepiride, sorafenib, and more. Hoechst S 769121 exhibits unique properties such as strong pyridinium emission and nuclear localization. This compound has shown promise in preclinical studies involving lenvatinib treatment and has been found to have interactions with phosphoric acid, diacetone, taurine, positron emission, and proton. Researchers are continuing to explore the potential uses and mechanisms of action of Hoechst S 769121 in various therapeutic areas.

Formula: C₂₅H₂₅N₇O₂S•(HCl)₃

Purity: Min. 95%

Molecular weight: 596.96 g/mol

Ref: 3D-ZCA68168