CAS 74682-62-5

Ticarcillin monosodium

Description:

Ticarcillin monosodium is a semisynthetic penicillin antibiotic that is primarily used to treat infections caused by susceptible Gram-negative bacteria. It is characterized by its ability to inhibit bacterial cell wall synthesis, which ultimately leads to cell lysis and death. Ticarcillin is particularly effective against Pseudomonas aeruginosa and other Enterobacteriaceae. The compound is typically administered via injection, as it is not well absorbed from the gastrointestinal tract. In terms of its chemical structure, ticarcillin contains a beta-lactam ring, which is essential for its antibacterial activity. The monosodium salt form enhances its solubility in aqueous solutions, making it suitable for parenteral administration. Common side effects may include allergic reactions, gastrointestinal disturbances, and potential disruption of normal flora. As with other antibiotics, the development of resistance is a concern, necessitating careful use and consideration of susceptibility patterns in clinical settings. Overall, ticarcillin monosodium is a valuable therapeutic agent in the management of serious infections caused by specific pathogens.

Formula: C₁₅H₁₄N₂Na₂O₆S₂

InChI: InChI=1/C15H16N2O6S2.Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);/q;+1/t7-,8-,9+,12-;/m1./s1

InChI key: InChIKey=GOPQWXUCPMVVFP-GHRKWLBTSA-N

SMILES: N(C([C@H](C(O)=O)C=1C=CSC1)=O)[C@H]2[C@@]3(N([C@@H](C(O)=O)C(C)(C)S3)C2=O)[H].[Na]

Synonyms:

• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-[2α,5α,6β(S*)]]-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-
• 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-
• <span class="text-smallcaps">D</span>-Ticarcillin sodium salt
• Ticarcillin monosodium
• Ticarcillin sodium
• D-Ticarcillin sodium salt
• TICARCILLIN DISODIUM
• (2S,5S,6R)-6-[[(2R)-CARBOXY-3-THIENYLACETYL]AMINO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3,2,0]HEPT
• (2S,5R,6R)-6-[[(2R)-2-carboxy-2-thiophen-3-yl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monosodium salt
• TICAR
• TRIARCILLINSODIUM
• timentin sodium
• TICARCILLIN DISODIUM SALT
• TIMENTIN
• (2S,5R,6R)-6-[[(2R)-2-carboxy-2-thiophen-3-yl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid disodium salt