CAS 747-36-4

Hydroxychloroquine sulfate

Description:

Hydroxychloroquine sulfate is an antimalarial and immunomodulatory medication primarily used to treat malaria, rheumatoid arthritis, and lupus erythematosus. It is a derivative of chloroquine and functions by interfering with the growth of parasites in the red blood cells. The compound is characterized by its ability to inhibit the lysosomal activity within cells, which is crucial for the survival of certain pathogens. Hydroxychloroquine sulfate is typically administered in oral form and is known for its relatively low toxicity profile compared to other antimalarials. Its chemical structure includes a 4-aminoquinoline moiety, which is essential for its pharmacological activity. The sulfate salt form enhances its solubility and stability. Common side effects may include gastrointestinal disturbances, skin reactions, and, in rare cases, retinal toxicity with prolonged use. Due to its immunomodulatory effects, hydroxychloroquine has gained attention in various off-label uses, particularly in autoimmune diseases. However, its efficacy and safety in these contexts continue to be the subject of ongoing research and clinical evaluation.

Formula: C₁₈H₂₆ClN₃O·H₂O₄S

InChI: InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

InChI key: InChIKey=JCBIVZZPXRZKTI-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)O.N(C(CCCN(CCO)CC)C)C=1C2=C(N=CC1)C=C(Cl)C=C2

Synonyms:

• 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate
• 2-([4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino)ethan-1-ol; sulfuric acid
• 7-Chloro-4-[4-N-ethyl-N-beta-hydroxyethylamino-1-methylbutylamino]quinoline sulfate
• 7-Chloro-4-[4-[ethyl(2-hydroxyethyl)amino]-1-methylbutylamino]-quinoline sulfate
• 7-chloro-4-({(1R)-4-[ethyl(2-hydroxyethyl)ammonio]-1-methylbutyl}amino)quinolinium
• 7-chloro-4-({(1S)-4-[ethyl(2-hydroxyethyl)ammonio]-1-methylbutyl}amino)quinolinium
• Ercoquin
• Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1)
• Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt)
• Ethanol, 2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt)
• Hydrochloroquine Sulfate
• Hydroxy chloroquine sulfate
• Hydroxychloroquine sulfate
• NSC 4375
• Plaquenil
• Plaquenil sulfate
• Quensyl

Hydroxychloroquine Sulfate

CAS: 118-42-3, 747-36-4

Formula: C₁₈H₂₆ClN₃O·H₂SO₄

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 433.95

Ref: 3B-H1306

Hydroxychloroquine Sulphate 1.0 mg/ml in Methanol (as free base)

CAS: 747-36-4

Color and Shape: Colourless

Ref: 61-AMP0764.00-01

Hydroxychloroquine Sulphate

CAS: 747-36-4

Color and Shape: Neat

Ref: 61-FOR0764.00

HYDROXYCHLOROQUINE SULFATE CRS

CAS: 747-36-4

HYDROXYCHLOROQUINE SULFATE CRS

Formula: C₁₈H₂₈ClN₃O₅S

Color and Shape: Modified

Molecular weight: 433.95

Ref: 41-Y0001839

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Formula: C₁₈H₂₆CIN₃OH₂SO₄

Purity: 99.7%

Color and Shape: White. To. Off-White

Molecular weight: 537.07944

Ref: 47-1100

HYDROXYCHLOROQUINE FOR SYSTEM SUITABILITY CRS

CAS: 747-36-4

HYDROXYCHLOROQUINE FOR SYSTEM SUITABILITY CRS

Formula: C₁₈H₂₈ClN₃O₅S

Color and Shape: White. Whitish. Crystalline Powder.

Molecular weight: 433.95

Ref: 41-Y0001841

Hydroxychloroquine Sulfate

CAS: 747-36-4

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Formula: C₁₈H₂₆ClN₃O·H₂O₄S

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 433.14382

Ref: 45-1327000

Hydroxychloroquine sulfate

CAS: 747-36-4

Formula: C₁₈H₂₈ClN₃O₅S

Purity: 99%

Color and Shape: Solid

Molecular weight: 433.9500

Ref: IN-DA0059P3

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.

Formula: C₁₈H₂₆ClN₃O·H₂SO₄

Purity: 98.92% - 99.88%

Color and Shape: Odorless Solid

Molecular weight: 433.95

Ref: TM-T0951

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Purity: ≥98%

Molecular weight: 433.95g/mol

Ref: 54-BUP16035

Hydroxychloroquine sulfate

CAS: 747-36-4

Formula: C₁₈H₂₆ClN₃O·H₂SO₄

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 433.95

Ref: 7W-GK2606

Hydroxychloroquine Sulfate

CAS: 747-36-4

Formula: C₁₈H₂₆ClN₃O·H₂O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 335.88 98.07

Ref: 4Z-H-061

Hydroxychloroquine Sulphate

CAS: 747-36-4

Color and Shape: Neat

Ref: 86-MM0764.00

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Formula: C₁₈H₂₆ClN₃O·H₂SO₄

Purity: 99%

Color and Shape: white solid

Molecular weight: 433.95g/mol

Ref: 54-BISN0145

Hydroxychloroquine Sulfate

Controlled Product

CAS: 747-36-4

Formula: C₁₈H₂₆ClN₃O·H₂O₄S

Color and Shape: Neat

Molecular weight: 433.95

Ref: TR-H916900

Hydroxychloroquine Sulfate

CAS: 747-36-4

Formula: C₁₈H₂₆ClN₃OH₂SO₄

Molecular weight: 335.9 : 98.1

Ref: ST-EA-CP-H4012

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic protozoan from the Plasmodium genus. Hydroxychloroquine is also used to treat non-infectious diseases such as rheumatoid arthritis and lupus thanks to its immunomodulatory properties. Recent studies revealed that hydroxychloroquine has beneficial effects on COVID-19 patients, as the current evidence shows that hydroxychloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the spike glycoprotein.

Formula: C₁₈H₂₆ClN₃O•H₂SO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 433.95 g/mol

Ref: 3D-FH24322

Hydroxychloroquine sulfate - Bio-X ™

CAS: 747-36-4

Hydroxychloroquine is a drug that is used to treat multiple types of autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus and discoid lupus. It is a prodrug, which is activated in the liver to hydroxychloroquine. It inhibits the production of inflammatory cytokines and nitric oxide by binding to the toll-like receptor 4 (TLR4) and inhibiting signaling pathways downstream of TLR4 activation. Additionally, Hydroxychloroquine is used to prevent and treat malaria caused by parasitic protozoan from the Plasmodium genus. Furthermore, recent studies revealed that hydroxychloroquine has beneficial effects on COVID-19 patients, as the current evidence shows that hydroxychloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the spike glycoprotein.

Formula: C₁₈H₂₈ClN₃O₅S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 433.95 g/mol

Ref: 3D-BH164525

2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol sulfate

CAS: 747-36-4

Formula: C₁₈H₂₈ClN₃O₅S

Purity: 95.0%

Color and Shape: Solid, White to slightly pale yellow powder

Molecular weight: 433.95

Ref: 10-F079411