CAS 747-45-5

Cinchonan-9-ol, 6′-methoxy-, (9S)-, sulfate (1:1)

Description:

Cinchonan-9-ol, 6′-methoxy-, (9S)-, sulfate (1:1), with the CAS number 747-45-5, is a chemical compound derived from cinchona alkaloids, which are known for their medicinal properties, particularly in the treatment of malaria. This compound features a cinchona backbone, characterized by a bicyclic structure that includes a quinoline moiety. The presence of a methoxy group at the 6′ position enhances its pharmacological activity. As a sulfate, it is likely to exhibit increased solubility in aqueous environments, which can influence its bioavailability and interaction with biological systems. The (9S) configuration indicates a specific stereochemistry that can be crucial for its biological function. Cinchonan-9-ol derivatives are often studied for their potential therapeutic effects, including antimalarial and analgesic properties. Overall, this compound exemplifies the complex interplay between structure and function in medicinal chemistry, highlighting the importance of stereochemistry and functional groups in drug design and efficacy.

Formula: C₂₀H₂₆N₂O₆S

InChI: InChI=1/C20H24N2O2.H2O4S/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4)/t13-,14?,19+,20-;/m0./s1

InChI key: InChIKey=AKYHKWQPZHDOBW-VJAUXQICSA-N

SMILES: S(=O)(=O)(O)O.[C@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@@]3([N@@]4C[C@H](C=C)[C@](C3)(CC4)[H])[H]

Synonyms:

• (9S)-6'-methoxycinchonan-9-ol sulfate (1:1)
• Biquin Durules
• Chinidin Duriles
• Chinidin VUFB
• Cinchonan-9-ol, 6′-methoxy-, (9S)-, sulfate (1:1)
• Cinchonan-9-ol, 6′-methoxy-, (9S)-, sulfate (1:1) (salt)
• Kinidin Duretter
• Kinidin Durules
• Kinilentin
• Optochinidin
• Quinidine bisulfate
• Quinidine hydrogen sulfate
• Quinidine, sulfate (1:1) (salt)
• Quiniduran
• Quinidine acid sulfate tetrahydrate
• chinidinvufb
• (9s)-6’-methoxycinchonan-9-olsulfate(1:1)(salt)
• (S)-(6-methoxy-4-quinolyl)-[(2R,5R)-5-vinylquinuclidin-2-yl]methanol
• Quinidine bisulphate
• 6’-methoxy-cinchonan-9-o(9s)-cinchonan-9-osulfate(1:1)(salt)
• kinidinduretter
• chinidinduriles
• kinidindurules
• (S)-[(5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol
• biquindurules
• quinidine hydrogen sulphate

Quinidine bisulfate

CAS: 747-45-5

Ref: 7W-GE7009

Quinidine Sulfate (>85%)

Controlled Product

CAS: 747-45-5

Applications Quinidine Sulfate, is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial.
References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 483 (1983), Mason, J. W., et al.: Ann. N. Y. Acad. Sci., 432, 162 (1984),

Formula: C₂₀H₂₄N₂O₂·H₂O₄S

Purity: >85%

Color and Shape: White To Off-White

Molecular weight: 422.495

Ref: TR-Q685040