CAS 74723-10-7

Nifoxipam

Description:

Nifoxipam is a chemical compound classified as a benzodiazepine derivative, primarily known for its anxiolytic and sedative properties. It is characterized by its ability to modulate the activity of gamma-aminobutyric acid (GABA) receptors in the central nervous system, leading to enhanced inhibitory neurotransmission. This mechanism contributes to its therapeutic effects, which may include anxiety reduction and muscle relaxation. Nifoxipam is typically administered in the form of tablets or capsules and is recognized for its relatively long half-life compared to other benzodiazepines, which can influence its duration of action. The compound is also noted for its potential side effects, which may include drowsiness, dizziness, and dependence with prolonged use. As with other benzodiazepines, caution is advised regarding its use, particularly in individuals with a history of substance abuse or certain medical conditions. Overall, Nifoxipam is a notable member of the benzodiazepine class, with specific pharmacological properties that make it useful in clinical settings.

Formula: C₁₅H₁₀FN₃O₄

InChI: InChI=1S/C15H10FN3O4/c16-11-4-2-1-3-9(11)13-10-7-8(19(22)23)5-6-12(10)17-14(20)15(21)18-13/h1-7,15,21H,(H,17,20)

InChI key: InChIKey=UHFIFTRHLBAWGY-UHFFFAOYSA-N

SMILES: FC1=C(C=2C=3C(=CC=C(N(=O)=O)C3)NC(=O)C(O)N2)C=CC=C1

Synonyms:

• Nifoxipam
• 5-(2-Fluorophenyl)-1,3-dihydro-3-hydroxy-7-nitro-2H-1,4-benzodiazepin-2-one
• 2H-1,4-Benzodiazepin-2-one, 5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-7-nitro-

3-Hydroxy Nor-Flunitrazepam

Controlled Product

CAS: 74723-10-7

Formula: C₁₅H₁₀FN₃O₄

Color and Shape: Neat

Molecular weight: 315.256

Ref: TR-H950085

3-Hydroxy Nor-Flunitrazepam (Nifoxipam) (1.0 mg/mL in Methanol)

Controlled Product

CAS: 74723-10-7

Formula: C₁₅H₁₀FN₃O₄

Color and Shape: Single Solution

Molecular weight: 315.256

Ref: TR-KIT7700

Nifoxipam

Controlled Product

CAS: 74723-10-7

Nifoxipam is a pharmaceutical drug that can be used to treat inflammatory diseases. It has been shown to reduce the levels of inflammatory cytokines and prostaglandin E2 in human serum. Nifoxipam is also an effective treatment for urinary tract infections, particularly in cases where the causative agent is Escherichia coli. This drug has been shown to have anti-cancer properties, which may be due to its ability to inhibit the growth of cancer cells. The hydroxyl group on nifoxipam can react with amino groups on proteins and form adducts that are excreted in urine samples. These adducts can be detected using analytical methods such as gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-mass spectrometry (LC-MS).

Formula: C₁₅H₁₀FN₃O₄

Purity: Min. 95%

Molecular weight: 315.26 g/mol

Ref: 3D-ZCA72310