CAS 74772-68-2

5-[[4-(2-Methyl-2-phenylpropoxy)phenyl]methyl]-2,4-thiazolidinedione

Description:

5-[[4-(2-Methyl-2-phenylpropoxy)phenyl]methyl]-2,4-thiazolidinedione, with CAS number 74772-68-2, is a synthetic organic compound that belongs to the thiazolidinedione class of drugs, which are primarily known for their role in the treatment of diabetes. This compound features a thiazolidinedione core, characterized by a five-membered ring containing sulfur and nitrogen, which is linked to a phenyl group substituted with a bulky 2-methyl-2-phenylpropoxy moiety. The structural complexity of this molecule contributes to its potential biological activity, particularly in modulating insulin sensitivity and glucose metabolism. Thiazolidinediones generally act as agonists of peroxisome proliferator-activated receptor gamma (PPAR-γ), influencing adipocyte differentiation and lipid metabolism. The compound's solubility, stability, and pharmacokinetic properties are influenced by its functional groups and overall molecular structure. As with many thiazolidinediones, it is essential to consider the potential side effects and contraindications associated with its use in clinical settings.

Formula: C₂₀H₂₁NO₃S

InChI: InChI=1S/C20H21NO3S/c1-20(2,15-6-4-3-5-7-15)13-24-16-10-8-14(9-11-16)12-17-18(22)21-19(23)25-17/h3-11,17H,12-13H2,1-2H3,(H,21,22,23)

InChI key: InChIKey=FZKKPKRWTSYXLF-UHFFFAOYSA-N

SMILES: C(C1SC(=O)NC1=O)C2=CC=C(OCC(C)(C)C3=CC=CC=C3)C=C2

Synonyms:

• 5-[[4-(2-Methyl-2-phenylpropoxy)phenyl]methyl]-2,4-thiazolidinedione
• AL 321 (peroxisome proliferator-activated receptor agonist)
• 2,4-Thiazolidinedione, 5-[[4-(2-methyl-2-phenylpropoxy)phenyl]methyl]-
• AL 321

TH1338

CAS: 74772-68-2

TH1338

Purity: ≥98%

Molecular weight: 391.42g/mol

Ref: 54-BUP20837

AL-321

CAS: 74772-68-2

AL-321 is a bio-active chemical. Detailed information has not been published. (Last Updated: 05/06/2016).

Formula: C₂₀H₂₁NO₃S

Color and Shape: Solid

Molecular weight: 355.45

Ref: TM-T29815