CAS 74784-45-5

[[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3R,4S,5R)-5-[(4R)-3-carbamoyl-4-deuterio-4H-pyridin-1-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

Description:

The chemical substance with the name "[[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3R,4S,5R)-5-[(4R)-3-carbamoyl-4-deuterio-4H-pyridin-1-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate" and CAS number "74784-45-5" is a complex organic molecule characterized by its intricate stereochemistry and functional groups. It features a tetrahydrofuran backbone, which is a five-membered cyclic ether, and incorporates multiple hydroxyl (-OH) groups, phosphonooxy, and phosphoryl functionalities, indicating its potential role in biochemical processes, possibly related to nucleotides or nucleosides. The presence of an aminopurine moiety suggests that it may interact with biological systems, potentially influencing nucleic acid metabolism or signaling pathways. The compound's chirality, denoted by its specific R and S configurations, implies that it may exhibit unique biological activities or interactions based on its stereochemistry. Overall, this substance is likely to be of interest in medicinal chemistry and biochemistry due to its structural complexity and potential biological relevance.

Formula: C₂₁H₂₉DN₇O₁₇P₃

InChI: InChI=1/C21H30N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35)/t10-,11-,13+,14+,15+,16+,20-,21-/m1/s1/i2D/t2-,10-,11-,13+,14+,15+,16+,20-,21-

b-Nicotinamide-D adenine dinucleotide reduced form

CAS: 74784-45-5

Ref: 7W-GN8620

β-NADPH-D

CAS: 74784-45-5

Formula: C₂₅H₂₉ClO₈

Molecular weight: 492.96

Ref: 4Z-N-076001

b-Nicotinamide-D adenine dinucleotide reduced form

Controlled Product

CAS: 74784-45-5

Nicotinamide-adenine dinucleotide (NADH) is a coenzyme that plays an essential role in cellular metabolism. NADH has been shown to have neuroprotective effects by improving cerebellar perfusion and reducing the severity of granule cell death in the cerebellum of experimental animals. It also inhibits synaptic activity and improves Purkinje cell survival. NADH is found in granules cells, which are located in the cerebellar cortex. These cells release this molecule when activated by an action potential, which leads to increased calcium levels inside neurons and subsequent neurotransmitter release. The major form of NADH found in these cells is NADH-NAD+ oxidoreductase (EC 1.6.5.3). The activity of this enzyme can be inhibited by a number of compounds, including nicotinamide adenine dinucleotide reduced form (NADH-NAD+ reductase), which may have therapeutic value for treating Parkinson's

Formula: C₂₁H₂₉N₇O₁₇P₃D

Purity: Min. 95%

Molecular weight: 746.43 g/mol

Ref: 3D-NN11407