CAS 74790-08-2

Spiroplatin

Description:

Spiroplatin, with the CAS number 74790-08-2, is a platinum-based antitumor agent that exhibits unique structural characteristics, distinguishing it from traditional platinum compounds like cisplatin. It features a spirocyclic structure, which contributes to its distinct mechanism of action and potential therapeutic efficacy. Spiroplatin is known for its ability to bind to DNA, leading to the formation of DNA cross-links that interfere with replication and transcription, ultimately triggering apoptosis in cancer cells. This compound has been studied for its activity against various types of tumors, including those resistant to conventional platinum therapies. Additionally, spiroplatin's solubility and stability in biological systems are critical factors influencing its pharmacokinetics and bioavailability. Research continues to explore its effectiveness, side effects, and potential applications in combination therapies, aiming to enhance its anticancer properties while minimizing toxicity. Overall, spiroplatin represents a promising avenue in the development of novel chemotherapeutic agents.

Formula: C₈H₁₈N₂O₄PtS

InChI: InChI=1S/C8H18N2.H2O4S.Pt/c9-6-8(7-10)4-2-1-3-5-8;1-5(2,3)4;/h1-7,9-10H2;(H2,1,2,3,4);/q;;+2/p-2

InChI key: InChIKey=XASGSSXPZXRXFL-UHFFFAOYSA-L

SMILES: O=S1(=O)[O-][Pt+2]2([O-]1)[NH2]CC3(C[NH2]2)CCCCC3

Synonyms:

• Sulfuric acid, platinum complex
• Platinum, (1,1-cyclohexanedimethanamine-N,N′)[sulfato(2-)-O,O′]-, (SP-4-2)-
• (SP-4-2)-(1,1-Cyclohexanedimethanamine-κN,κN′)[sulfato(2-)-κO,κO′]platinum
• 1,1-Cyclohexanedimethanamine, platinum complex
• Platinum, (1,1-cyclohexanedimethanamine-κN,κN′)[sulfato(2-)-κO,κO′]-, (SP-4-2)-

Spiroplatin

CAS: 74790-08-2

Spiroplatin (TNO-6) is a novel platinum-containing analogue with antitumor activity that is commonly used in the study of solid tumors.

Formula: C₈H₁₈N₂O₄PtS

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 433.39

Ref: TM-T68144